HEPATOBLASTOMA
Clinical trials for HEPATOBLASTOMA explained in plain language.
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Supercharged immune cells take on hard-to-treat cancers
Disease control Recruiting nowThis early-phase trial tests a new type of immunotherapy for adults with solid tumors that have a protein called GPC3 on their surface. Researchers take a patient's own T cells, add genes to help them recognize and attack GPC3-positive cancer cells, and also include a safety swit…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 26, 2026 04:06 UTC
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Engineered immune cells take on childhood cancers in new trial
Disease control Recruiting nowThis early-stage trial tests a new treatment for children and young adults with solid tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells. The m…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 26, 2026 04:02 UTC
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New hope for kids with relapsed cancers: experimental drug combo enters human testing
Disease control Recruiting nowThis study tests a mix of four drugs (vorinostat, vincristine, irinotecan, and temozolomide) in children, teens, and young adults up to age 30 whose solid tumors or brain cancers have returned or not responded to standard treatment. The main goal is to find the safest dose of vor…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: New York Medical College • Aim: Disease control
Last updated May 26, 2026 03:51 UTC
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New hope for kids with tough liver cancer: triple-drug combo enters trial
Disease control Recruiting nowThis study tests a combination of three drugs (pucotenlimab, lenvatinib, and irinotecan) in children aged 2-18 with advanced hepatoblastoma that has relapsed or not responded to prior therapy. The goal is to see if this new mix can slow or stop the cancer. About 24 children will …
Matched conditions: HEPATOBLASTOMA
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New hope for kids with rare liver cancer: smarter chemo combo under study
Disease control Recruiting nowThis study tests a new chemotherapy plan for children and teens with hepatoblastoma, a rare liver cancer. The goal is to improve survival, especially for high-risk patients who currently have only a 40% chance of living. Researchers will also use a simple blood test to monitor th…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Engineered immune cells take on childhood cancers in new trial
Disease control Recruiting nowThis early-stage trial tests a personalized cell therapy for children and young adults (up to age 21) with solid tumors that have come back or not responded to standard treatment. Doctors take the patient's own immune cells, modify them to recognize a protein called B7-H3 on tumo…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New hope for rare cancers: immunotherapy trial targets tumors regardless of origin
Disease control Recruiting nowThis study tests the drug nivolumab in people with advanced rare cancers that have a specific marker (PD-L1). The goal is to see if the drug can shrink or control tumors for at least 12 months. About 28 adults who have not responded to standard treatments will take part.
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: Instituto do Cancer do Estado de São Paulo • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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Scientists dive into DNA of Kids' liver tumors to unlock secrets
Knowledge-focused Recruiting nowThis study aims to uncover the genetic and molecular causes of liver cancer in children. Researchers will analyze DNA, gene activity, and other markers from up to 1,600 participants, including children with liver tumors and their biological relatives. The goal is to better classi…
Matched conditions: HEPATOBLASTOMA
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC