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Massive study aims to decode genetic secrets of pediatric liver tumors

NCT ID NCT03959800

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 37 times

Summary

This study is collecting genetic and molecular data from up to 1,600 children with liver cancer and their families. Researchers will analyze DNA, gene activity, and immune cells in tumors to better understand how these cancers develop. The goal is to improve how doctors classify and treat childhood liver cancers in the future.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could lead to better classification and understanding of childhood liver cancers, potentially guiding future treatments.

What could go wrong

This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may take years to impact patient care.

Conditions

The condition(s) this trial relates to.

hepatoblastoma hepatocellular carcinoma liver cancer rhabdoid tumor undifferentiated embryonal sarcoma of the liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.