HEPATOBLASTOMA
Clinical trials for HEPATOBLASTOMA explained in plain language.
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Immune cells engineered to fight childhood cancers enter first human tests
Disease control OngoingThis early-phase study tests a new treatment for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein c…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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New hope for kids with liver cancer: international trial tests smarter chemo cocktails
Disease control OngoingThis study tests different combinations of chemotherapy drugs in children and young adults with liver cancer (hepatoblastoma or hepatocellular carcinoma). The goal is to see which combinations work best alongside surgery to stop tumors from growing or spreading. About 537 partici…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE3 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated May 26, 2026 08:38 UTC
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New flavored chemo drink offers hope for kids with hard-to-treat cancers
Disease control OngoingThis early-stage study tests a flavored, drinkable chemotherapy called VAL-413 (Orotecan) for children and young adults (ages 1-30) whose solid tumors have come back. The drug is given by mouth along with another chemo, temozolomide, for 5 days. The main goal is to find the safes…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Valent Technologies, LLC • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New hope for kids with rare cancers: drug blocks tumor growth
Disease control OngoingThis study tests a daily pill called cabozantinib in children and young adults (up to age 30) with rare cancers like sarcomas, Wilms tumor, and others that have come back or not responded to treatment. The drug works by blocking signals that help tumors grow and form blood vessel…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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Engineered immune cells take aim at childhood cancers in early trial
Disease control OngoingThis early-phase study tests a personalized cell therapy for children and young adults (ages 1–30) whose solid tumors have come back or not responded to standard treatment. Researchers take a patient's own immune T cells, modify them to recognize and attack cancer cells that carr…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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New immunotherapy combo shows promise for young cancer patients
Disease control OngoingThis study tests two immunotherapy drugs, cobolimab and dostarlimab, together in children and young adults (up to age 21) with advanced solid tumors that have not responded to other treatments. The goal is to find the safest dose and see if the combination can shrink tumors. The …
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated May 22, 2026 13:50 UTC