5,000 volunteers join hunt for brain disease clues
NCT ID NCT03592563
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This long-term study is tracking 5,000 adults in Hong Kong who either have a brain disease (like stroke or dementia) or are at high risk due to family history or early signs. Researchers will collect medical records and questionnaires every 6 months to find what factors lead to brain diseases. The goal is to learn how to preserve brain health, but no treatment or drug is being tested.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal key risk factors for brain diseases like stroke and dementia, pointing toward better prevention strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It may take years to yield clear results, and findings might not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2019
- Expected to finish
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Dec 2048
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
1. Chinese ONLY 2. Hong Kong Resident
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adult ≥ 18 years of age 2. Fulfilling criteria for membership in one of these three groups: * Red group: established diagnosis of one or more neurological and/or psychiatric conditions * Yellow group: high-risk to develop one or more neurological and/or psychiatric conditions 1. family history (first degree relative) one or more neurological and/or psychiatric conditions 2. examination, imaging or laboratory findings consistent with pre-symptomatic stages of one or more neurological and/or psychiatric disorders * Green group: not meeting criteria for Red or Yellow groups, but interested in longitudinal research on maintenance and/or improvement of brain health 3. Subject provides informed consent by signing and dating the written informed consent form 4. Subject is willing to answer health questionnaires and be followed longitudinally Exclusion Criteria: * None
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Chinese University of Hong Kong
RECRUITINGHong Kong, Hong Kong
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The Chinese University of Hong Kong
RECRUITINGHong Kong, Hong Kong
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