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Freezing tumors may boost radiation pain relief for bone metastases

NCT ID NCT04693377

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 39 times

Summary

This study tests whether adding a freezing procedure called cryoablation to standard radiation therapy can better relieve pain from cancer that has spread to the bones. About 40 adults with certain cancers (like prostate, kidney, or melanoma) that have spread to the bone will be enrolled. Half will get radiation alone, and half will get both cryoablation and radiation, to see which approach provides more pain relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma colorectal cancer colorectal carcinoma colorectal neoplasm melanoma metastatic carcinoma in the bone metastatic malignant neoplasm metastatic melanoma metastatic prostate carcinoma Neoplasm Metastasis prostate cancer renal cell adenocarcinoma renal cell carcinoma sarcoma thyroid gland carcinoma Thyroid Neoplasms transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.