METASTATIC SARCOMA

This study is testing an oral medication called avapritinib for people with advanced solid tumors that have spread and have specific genetic changes (mutations in the CKIT or PDGFRA genes). The drug aims to block the signals that help these tumor cells grow, potentially controlli…

This early-stage study is testing a new combination of two drugs, peposertib and liposomal doxorubicin, for people with advanced soft tissue sarcomas that have spread or cannot be removed by surgery. The main goal is to find the safest and most effective dose of this drug pair. R…

This study is testing a checklist tool designed to help people with sarcoma plan for their future mobility needs. Researchers want to see if using this planning tool is helpful and easy for patients and their caregivers to use. The goal is to improve quality of life by helping pe…

This study is testing if adding a freezing procedure (cryoablation) to standard radiation therapy works better to relieve pain from cancer that has spread to the bones. Researchers will compare the combination treatment to radiation alone in 40 patients with advanced cancers. The…

This early study is testing a tiny, rice-sized device that can be implanted into a sarcoma tumor. The device releases tiny amounts of 10 different cancer drugs directly into the tumor tissue. The goal is to see which drugs affect the tumor cells, helping doctors learn which treat…

This study aims to learn more about the tiny blood vessels that feed solid tumors. Researchers will use a special microscope during a patient's standard cancer surgery to see these vessels in real time. The goal is to understand how tumor blood flow works and if it relates to how…