STAGE IVB PROSTATE CANCER AJCC V8
Clinical trials for STAGE IVB PROSTATE CANCER AJCC V8 explained in plain language.
Never miss a new study
Get alerted when new STAGE IVB PROSTATE CANCER AJCC V8 trials appear
Sign up with your email to follow new studies for STAGE IVB PROSTATE CANCER AJCC V8, keep track of the ones that matter, and come back to a personal dashboard instead of checking manually.
Genom att skicka in godkänner du våra Användarvillkor
-
Could treating the primary tumor boost survival in advanced prostate cancer?
Disease control Recruiting nowThis study compares standard drug therapy alone versus standard therapy plus surgery or radiation to the prostate in men whose cancer has spread. The goal is to see if treating the original tumor improves overall survival. About 1,273 participants will be enrolled.
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 01, 2026 14:37 UTC
-
New hope for rare cancers: Triple-Drug attack shows promise
Disease control Recruiting nowThis study is testing a combination of three drugs (cabozantinib, nivolumab, and ipilimumab) in people with rare genitourinary cancers that have spread. The goal is to see if this mix can shrink tumors better than any single drug alone. About 314 adults with these rare cancers wi…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 01, 2026 14:34 UTC
-
New drug combo shows promise in halting prostate cancer growth
Disease control Recruiting nowThis study tests whether adding a targeted drug called talazoparib to standard hormone therapy can better control prostate cancer that has spread but still responds to hormones. About 70 men with metastatic castration-sensitive prostate cancer will receive the combination. The go…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 01, 2026 14:33 UTC
-
Triple threat: new combo aims to extend lives in prostate cancer
Disease control Recruiting nowThis study tests whether adding a chemotherapy drug (docetaxel) to the usual hormone therapy and apalutamide can help men with prostate cancer that has spread. About 1,260 participants will receive either the standard two-drug treatment or the three-drug combination. The goal is …
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 01, 2026 14:33 UTC
-
Could high testosterone boost chemo against tough prostate cancer?
Disease control Recruiting nowThis study tests whether giving high levels of testosterone alongside chemotherapy or a targeted radiation drug can help men with advanced prostate cancer that has stopped responding to standard hormone therapy. About 69 participants will receive testosterone injections plus eith…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
-
New combo therapy aims to boost immune attack on hard-to-treat prostate cancer
Disease control Recruiting nowThis early-phase trial studies whether adding a targeted radiation drug (Lu-PSMA-617) to an immune cell therapy (Sipuleucel-T) is safe and works better than the radiation drug alone for men with metastatic castration-resistant prostate cancer. About 30 participants will receive e…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
-
Second dose of radioactive drug shows promise for tough prostate cancer
Disease control Recruiting nowThis study tests whether giving a second round of a radioactive drug called 177Lu-PSMA-617 can help men with advanced prostate cancer that no longer responds to hormone therapy. The drug targets and delivers radiation directly to cancer cells. Participants must have already respo…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
-
New hope for Hard-to-Treat prostate cancer? drug combo trial begins
Disease control Recruiting nowThis study tests a combination of two drugs, ruxolitinib and enzalutamide, in men with advanced prostate cancer that has spread and no longer responds to standard hormone therapy. The goal is to find the safest dose and see if the combo can shrink tumors or lower PSA levels. Abou…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
-
PET scans guide smarter prostate cancer treatment in major new trial
Disease control Recruiting nowThis study is for men whose prostate cancer has returned after surgery, shown by a rising PSA level. It tests whether adding a stronger drug combination (apalutamide plus abiraterone and prednisone) to standard radiation and hormone therapy can delay cancer progression. For men w…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
-
Could less be more? new trial pauses prostate cancer therapy after 5 doses
Disease control Recruiting nowThis study looks at whether men with advanced prostate cancer that has spread can safely stop a targeted radiation drug (Lu-177 PSMA-617) after 5 cycles instead of the usual 6. About 236 participants will be randomly assigned to either a treatment pause or continuous therapy. The…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
-
New combo aims to make resistant prostate cancer cells visible to targeted radiation
Disease control Recruiting nowThis study tests whether the drug vorinostat can help men with a type of advanced prostate cancer that has low levels of a specific marker (PSMA). The marker is needed for a radioactive therapy called 177Lu-PSMA-617 to work. By giving vorinostat first, the hope is to increase PSM…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
-
New trial aims to sharpen prostate cancer treatment with PET-Guided radiation
Disease control Recruiting nowThis study tests whether adding PET-guided radiation to standard hormone therapy can better control metastatic prostate cancer. About 125 men with hormone-sensitive prostate cancer that has spread will be randomly assigned to receive standard treatment alone or with targeted radi…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
-
Triple-Drug attack shows promise for Hard-to-Treat prostate cancer
Disease control Recruiting nowThis study tests whether adding two new drugs (M3814 and avelumab) to standard radium-223 therapy can better control advanced prostate cancer that has spread to bones. About 90 men with castration-resistant prostate cancer will receive either radium-223 alone or with one or both …
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
-
Freezing tumors could double pain relief for bone metastases patients
Symptom relief Recruiting nowThis study tests whether adding cryoablation (freezing cancer cells) to standard radiation therapy provides better pain relief for people with cancer that has spread to their bones. About 40 adults with advanced cancers like prostate, colorectal, or melanoma will be randomly assi…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 14:31 UTC
-
Tailored care plans aim to bridge health literacy gap for black prostate cancer survivors
Knowledge-focused Recruiting nowThis study compares a standard survivorship care plan to one tailored for low health literacy in 150 African American men who have finished treatment for prostate cancer. The goal is to see if the tailored plan helps them better understand their follow-up care and side effects. R…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 01, 2026 14:37 UTC
-
Gene test could guide prostate cancer treatment choices
Knowledge-focused Recruiting nowThis study is for people with advanced prostate cancer that no longer responds to hormone therapy. It tests whether analyzing the DNA and RNA of a patient's tumor can help doctors pick the most effective treatment from several options, including targeted drugs and chemotherapy. T…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Knowledge-focused
Last updated May 01, 2026 14:32 UTC
-
Can DNA glitches predict prostate cancer treatment success?
Knowledge-focused Recruiting nowThis study looks at men with advanced prostate cancer that has spread to the bones. Researchers want to see if certain DNA repair problems make the drug radium-223 work better. About 48 men will take part, and the goal is to help doctors choose the best treatment in the future.
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC