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New combo therapy aims to boost immune attack on Hard-to-Treat prostate cancer

NCT ID NCT07219147

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 34 times

Summary

This early-phase study tests whether adding an immune-boosting vaccine (Sipuleucel-T) to a radioactive drug (Lu-PSMA) is safe and works better than the radioactive drug alone for men with advanced prostate cancer that has spread and stopped responding to hormone therapy. About 30 men will take part. The goal is to see if the combination can help the immune system better recognize and kill cancer cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.