STAGE IVB PROSTATE CANCER AJCC V8
Clinical trials for STAGE IVB PROSTATE CANCER AJCC V8 explained in plain language.
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Prostate cancer breakthrough: pausing treatment may restore testosterone
Disease control OngoingThis study looks at whether men whose metastatic prostate cancer has responded very well to hormone therapy can safely take a break from treatment. The goal is to see if pausing therapy allows their testosterone levels to return to normal while keeping the cancer under control. A…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 01, 2026 15:28 UTC
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New drug targets hard-to-treat prostate cancer with specific gene mutation
Disease control OngoingThis study tests a drug called M1774 in 20 men with advanced prostate cancer that has a specific genetic change (SPOP mutation) and is no longer responding to standard treatments. The drug works by blocking certain enzymes that cancer cells need to grow. The goal is to see if M17…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 01, 2026 15:28 UTC
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New combo therapy targets hard-to-treat cancers in early trial
Disease control OngoingThis early-phase study tests a new drug (DS3201) combined with an immunotherapy (ipilimumab) in 65 people with advanced prostate, bladder, or kidney cancer that has spread. The main goals are to find the safest dose and check side effects. Researchers hope this combination can he…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 01, 2026 15:28 UTC
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New combo therapy shows promise for tough prostate cancer
Disease control OngoingThis study tests a powerful mix of hormone-blocking drugs (apalutamide, abiraterone, and prednisone) given after chemotherapy for men with advanced prostate cancer that has spread. The goal is to see if this combination can lower PSA levels more effectively. The study also looks …
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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New drug combo aims to control spread of prostate cancer
Disease control OngoingThis study tests a three-drug combination (abiraterone, prednisone, and apalutamide) in 60 men with prostate cancer that has spread but hasn't yet been treated with hormone therapy. The goal is to see how long the treatment can control the cancer. Participants must have high-risk…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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New combo therapy aims to halt spread of prostate cancer
Disease control OngoingThis study tests whether adding the drug relugolix to standard radiation therapy can better control prostate cancer that has spread to a few other body spots. Relugolix lowers testosterone, which can fuel cancer growth. About 194 men with this type of cancer will receive either r…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC