New combo aims to boost radiation therapy for advanced prostate cancer
NCT ID NCT05113537
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 23 times
Summary
This study tests whether giving a drug called abemaciclib before a targeted radiation therapy (177Lu-PSMA-617) can make the radiation work better for men with advanced prostate cancer that has stopped responding to other treatments. About 30 participants will receive the combination to find the safest dose and see if it improves tumor shrinkage. The goal is to increase the cancer cells' uptake of the radioactive drug, potentially killing more tumor cells.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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