STAGE IVA PROSTATE CANCER AJCC V8
Clinical trials for STAGE IVA PROSTATE CANCER AJCC V8 explained in plain language.
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Could treating the primary tumor boost survival in advanced prostate cancer?
Disease control Recruiting nowThis study compares standard drug therapy alone versus standard therapy plus surgery or radiation to the prostate in men whose cancer has spread. The goal is to see if treating the original tumor improves overall survival. About 1,273 participants will be enrolled.
Matched conditions: STAGE IVA PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 01, 2026 14:37 UTC
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New drug combo aims to stop prostate cancer spread in high-risk patients
Disease control Recruiting nowThis study tests whether adding the drug apalutamide to standard hormone therapy and radiation helps men with prostate cancer that has spread to lymph nodes after surgery. About 586 participants will receive either the usual treatment or the usual treatment plus apalutamide. The …
Matched conditions: STAGE IVA PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 01, 2026 14:35 UTC
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New drug combo shows promise in halting prostate cancer growth
Disease control Recruiting nowThis study tests whether adding a targeted drug called talazoparib to standard hormone therapy can better control prostate cancer that has spread but still responds to hormones. About 70 men with metastatic castration-sensitive prostate cancer will receive the combination. The go…
Matched conditions: STAGE IVA PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 01, 2026 14:33 UTC
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Could a new pill help men with aggressive prostate cancer stay Cancer-Free longer?
Disease control Recruiting nowThis study is for men with high-risk prostate cancer that hasn't spread far. It tests whether adding the drug niraparib after standard radiation and hormone therapy can keep the cancer from coming back longer. About 200 men will take part, and the study compares standard hormone …
Matched conditions: STAGE IVA PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 01, 2026 14:33 UTC
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New scan may spare prostate cancer patients from unnecessary surgery
Diagnosis Recruiting nowThis study tests whether a combined PET/MRI scan using a radioactive tracer can accurately detect if prostate cancer has spread to nearby lymph nodes. About 50 men with high-risk prostate cancer scheduled for prostate removal will get the scan before surgery. The goal is to see i…
Matched conditions: STAGE IVA PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated May 01, 2026 14:36 UTC
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Freezing tumors could double pain relief for bone metastases patients
Symptom relief Recruiting nowThis study tests whether adding cryoablation (freezing cancer cells) to standard radiation therapy provides better pain relief for people with cancer that has spread to their bones. About 40 adults with advanced cancers like prostate, colorectal, or melanoma will be randomly assi…
Matched conditions: STAGE IVA PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 14:46 UTC