Brain training games tested for memory and mood in seniors

NCT ID NCT07598409

Knowledge-focused Sponsor: Universidad Antonio de Nebrija Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a series of online brain games (CogniFit) can improve memory, thinking skills, and emotional well-being in healthy older adults and those with mild cognitive impairment (MCI). Researchers will compare trained and untrained groups to see if any benefits transfer to everyday life. The trial involves 156 participants aged 65 and older in Spain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: Computerized cognitive training (CogniFit platform)
What this could lead to: If it works, this could point toward a simple, non-drug way to boost memory and emotional well-being in older adults, especially those with mild cognitive impairment.
What could go wrong: This is a small, early-stage study. The training may only improve the specific games played, not real-world memory or mood. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 156 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. adults 65 years of age and older; 2. spanish speakers; 3. residents in Spain (urban and rural communities); 4. elderly population that does not have dementia or other major diagnosed uncontrolled neurological disorders; 5. the initial cognitive state will be determined by a global screening test, the Lobo's Mini Cognitive Examination, that is, the spanish version of the Mini-Mental State Examination (MMSE); and 6) all participants must provide their signed written informed consent indicating that the individual has been informed of the relevant aspects of the study (and may withdraw from the study at any time if they so request). Exclusion Criteria: 1. Older adults who obtain scores indicative of severe impairment (to be determined for low MEC scores that are suggestive of incipient dementia) or whose medical condition prevents them from participating safely; 2. diagnosis of dementia (e.g., Alzheimer's disease or other); 3. uncontrolled active major psychiatric illness (major depression, schizophrenia, etc.); 4. significant uncontrolled neurological conditions or history (e.g., Parkinson's disease, stroke, severe traumatic brain injury); 5. uncontrolled decompensated chronic medical conditions (e.g., diabetes, cardiovascular disease) that may affect cognition or attendance at sessions; and 6) severe uncorrected sensory disabilities (e.g., blindness or severe hearing loss) that interfere with the performance of tasks on tablets.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy aging Mild cognitive impairment (MCI)

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

2 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Brain training games tested for memory and mood in seniors

What the study statuses mean