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Can a lifestyle coach lower your risk of stroke and dementia?

NCT ID NCT07755631

Prevention Sponsor: Andrew Appleton Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 26, 2026 · Updated 5 times

Summary

This pilot study tests a lifestyle intervention called BASIC-S, which uses coaching, text messages, and video check-ins to help people improve blood pressure, activity, sleep, social connection, nutrition, and support. The goal is to see if this approach is feasible and acceptable for reducing vascular risk factors that can lead to stroke, heart disease, and dementia. Participants are adults employed at or retired from a specific health center, along with their partners, and will be randomly assigned to either the intervention or standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A behavioral intervention combining wellness coaching, digital workbook, motivational text messages, and video booster sessions to support lifestyle changes.
What this could lead to
If successful, this program could offer a practical, scalable way to help people lower their risk of stroke, heart disease, and dementia through lifestyle changes.
What could go wrong
This is a small pilot study focused on feasibility, not effectiveness. The intervention may not produce significant health improvements, and results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years and older currently employed at or recently retired from the London Health Sciences Centre (LHSC) or Western University (with an operational focus on pre-retirees aged 50 years and older). * The primary applicant (not their partner, if applicable) must be within two years before or after their retirement date. * Spouse or cohabitating partner of an enrolled primary participant. Cohabitating partners may include a common-law partner, adult child, close friend, or roommate who lives with the primary participant and shares common health goals. Enrollment of partners is optional but strongly encouraged. * Capable of providing informed consent. * Has access to a mobile device capable of receiving Short Message Service (SMS) communications and viewing Portable Document Format (PDF) documents. * Physically able to safely engage in light-to-moderate intensity physical activity. Exclusion Criteria: * Medical conditions that preclude safe participation in physical activity (for instance, unstable angina, uncontrolled arrhythmia, severe heart failure) without physician clearance. * Active or unstable psychiatric illness, defined as hospitalization for psychiatric care within the preceding 6 months or modifications to antipsychotic or mood-stabilizing pharmacotherapy within the preceding 3 months. Participants with stable, medically managed psychiatric conditions remain eligible. * Severe cognitive impairment that compromises the ability to provide informed consent or independently use study-related technology. * Inability to read and understand English sufficiently to provide informed consent and complete study procedures.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction dementia hypertensive disorder Motor Activity Psychological Well-Being Social Isolation stroke disorder vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular risk factor Cognitive decline Dementia Hypertension (HTN) Stroke Vascular diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • London Health Sciences Centre (LHSC)

    London, Ontario, N6A 3K7, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.