Yale University
Clinical trials sponsored by Yale University, explained in plain language.
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Drug duo tested to fight cancer that spread to the brain
Disease control TerminatedThis study tested whether a combination of two drugs, pembrolizumab and lenvatinib, could shrink tumors in the brain for patients with melanoma or kidney cancer that had spread there. The trial was for patients whose cancer had worsened despite previous immunotherapy. The main go…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Heart drug tested as potential lifeline for severe alcohol hepatitis
Disease control TerminatedThis study tested whether digoxin, a medication normally used for heart conditions, could help control severe liver inflammation caused by heavy alcohol use. It involved 23 hospitalized patients with severe alcohol-associated hepatitis, who were randomly assigned to receive eithe…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Mar 10, 2026 12:53 UTC
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Smart band vs. classic buzzer: which stops bedwetting better?
Symptom relief TerminatedThis study aimed to see if a newer, wearable bedwetting alarm (GoGoband) works better than a standard alarm. Children and teens with bedwetting were randomly assigned to use one of the two devices for three months to compare how many dry nights they achieved. The trial was termin…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Scientists zap brain to unlock speech learning secrets
Knowledge-focused TerminatedThis Yale University study aimed to understand how the brain's memory systems help us learn new speech patterns. Researchers used a safe, non-invasive magnetic stimulation technique on healthy adults to temporarily reduce activity in a specific memory area of the brain. They then…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Can a positive pep talk boost depression treatment?
Knowledge-focused TerminatedThis study aimed to see if a patient's mindset and expectations could improve the effectiveness of esketamine, a fast-acting treatment for depression. Researchers tested whether a positive presentation before treatment and a supportive follow-up session could make the treatment w…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists zap brains to unlock speech memory secrets
Knowledge-focused TerminatedThis Yale University study aimed to understand how different parts of the brain help us form lasting memories for speech movements. Researchers used a safe, non-invasive magnetic stimulation technique on healthy adults right after they practiced speaking with altered feedback. Th…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Can feeling your face move change how you hear speech?
Knowledge-focused TerminatedThis Yale University study explored whether pairing touch sensations with speech sounds during practice changes how people perceive those sounds. Researchers worked with 160 healthy right-handed adults, measuring changes in both speech production and perception on simple scales. …
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC