West Virginia University

This study tests whether adding hydroxychloroquine (a malaria drug) to standard chemotherapy before surgery can improve outcomes for people with resectable pancreatic cancer. About 40 participants will receive the drug combo, then undergo surgery to remove their tumor. The goal i…

This study is for people with blood cancers like leukemia who are getting chemotherapy or a stem cell transplant, which can cause very low white blood cell counts (neutropenia) for over a week. The goal is to see if the antibiotic eravacycline can prevent serious bacterial infect…

This study tests whether giving heated chemotherapy directly into the abdomen during surgery is safe for people with high-risk gallbladder cancer. The treatment aims to prevent cancer from coming back in the belly lining. Ten participants will be enrolled to check for complicatio…

This study is for people with myelodysplastic syndromes (MDS) whose disease has returned or not responded to standard treatment. Researchers are testing a combination of two drugs, leflunomide and decitabine, to find the safest and most effective doses. The goal is to control the…

This study tests a subcutaneous (under-the-skin) form of blinatumomab for adults with a rare, aggressive leukemia called CD19-positive mixed phenotype acute leukemia (MPAL). It includes three groups: newly diagnosed patients who cannot tolerate strong chemotherapy, patients in re…

This study looks at whether a simple, twice-weekly resistance exercise program using bands can help manage fatigue in breast cancer survivors. Researchers will enroll 60 women from different income backgrounds to see if the program is practical and who sticks with it. The goal is…

This early study tests whether adding aluminum chloride, a drug that stops bleeding, to a standard 5-fluorouracil cream works better for treating actinic keratoses—rough, scaly spots from sun exposure that can turn into skin cancer. Thirty-two adults with these spots on their sca…

This study tests a nurse-led home care program for people with advanced heart failure and their family caregivers in rural Appalachia. The program uses faith-based nurses and local volunteers to improve quality of life and reduce symptoms. About 208 patients and their caregivers …

This study is testing whether injecting cooled or warmed salt water (saline) directly into lipomas—harmless fatty lumps under the skin—can shrink them. About 20 adults with at least one lipoma will receive up to four treatments, each four weeks apart. The goal is to see if this s…

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce impulse control disorders in people with Parkinson's disease who take dopamine medications. Twenty participants will receive both real and sham stimulation in random order, then complete ta…

This registry will follow 50 adults undergoing endoscopic ultrasound (EUS)-guided radiofrequency or microwave ablation for pancreatic or other gastrointestinal lesions as part of their routine care. Researchers will track changes in tumor size, survival, tumor markers, and side e…

This study adapts a suicide risk screening program called the NIMH Clinical Pathway for use in two school-based health centers in rural West Virginia. Researchers will work with 30 participants—students, parents, and providers—to see if the program is practical and effective at i…

This study looks at how different doses of CBD oil affect driving performance in 300 healthy adults aged 18-30. Participants will take CBD or a placebo and then use a driving simulator to measure weaving, crashes, and reaction time. The goal is to understand if CBD causes drowsin…

This study looks at whether filtering out blue light at night in hospital rooms can reduce inflammation, protect thinking skills, and improve mood and sleep in 80 adults having elective heart surgery. Participants will be randomly assigned to wear blue-blocking glasses or regular…