West Virginia University

This study is for people with blood cancers like leukemia who are getting chemotherapy or a stem cell transplant, which can cause very low white blood cell counts (neutropenia) for over a week. The goal is to see if the antibiotic eravacycline can prevent serious bacterial infect…

This study tests whether giving heated chemotherapy directly into the abdomen during surgery is safe for people with high-risk gallbladder cancer. The treatment aims to prevent cancer from coming back in the belly lining. Ten participants will be enrolled to check for complicatio…

This study is for people with myelodysplastic syndromes (MDS) whose disease has returned or not responded to standard treatment. Researchers are testing a combination of two drugs, leflunomide and decitabine, to find the safest and most effective doses. The goal is to control the…

This study tests whether adding hydroxychloroquine (a malaria drug) to standard chemotherapy before and after surgery can improve outcomes for people with resectable pancreatic cancer. About 40 participants will receive the combination, then undergo surgery if possible. The goal …

This study tests a subcutaneous (under-the-skin) form of blinatumomab for adults with a rare, aggressive leukemia called CD19-positive mixed phenotype acute leukemia (MPAL). It includes three groups: newly diagnosed patients who cannot tolerate strong chemotherapy, patients in re…

This study looks at whether filtering out blue light at night in hospital rooms can help people recover after heart surgery. Researchers will check if it reduces inflammation, improves thinking, mood, and sleep. About 80 adults having elective heart surgery will take part. If it …

This study looks at whether a simple strength training program can help breast cancer survivors manage fatigue. Researchers will work with 60 women from different backgrounds to see if factors like income and support affect how well they stick with the program. The goal is to fin…

This study tests a nurse-led home care program for people with advanced heart failure and their family caregivers in rural Appalachia. The program uses faith-based nurses and local volunteers to improve quality of life and reduce symptoms. About 208 patients and their caregivers …

This study is testing whether injecting cooled or warmed salt water (saline) directly into lipomas—harmless fatty lumps under the skin—can shrink them. About 20 adults with at least one lipoma will receive up to four treatments, each four weeks apart. The goal is to see if this s…

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce impulse control disorders in people with Parkinson's disease who take dopamine medications. Twenty participants will receive both real and sham stimulation in random order, then complete ta…

This study tests whether adding aluminum chloride hexahydrate to a standard prescription cream (5-fluorouracil) works better at removing actinic keratoses—rough, scaly spots from sun exposure that can turn into skin cancer. About 32 adults with 4-15 spots on their scalp or forear…

This study is a registry that follows 50 adults who are already scheduled to have a procedure called EUS-guided ablation (using heat or microwaves) to treat abnormal growths in the pancreas or other digestive organs. The goal is to collect information on how well the treatment sh…

This study is testing a program to help school-based health clinics in rural West Virginia routinely screen teenagers for suicide risk. Researchers will work with providers, parents, and youth to adapt the program to fit local needs. About 30 teens will take part to see if the sc…

This study looks at how non-prescription CBD affects driving performance, drowsiness, and thinking in 300 healthy adults aged 18-30. Participants will use a driving simulator to measure weaving, crashes, and reaction time after taking different doses of CBD. The goal is to unders…