Could a bleeding stopper boost a skin spot cream?

NCT ID NCT07401277

Recruiting now Symptom relief Sponsor: West Virginia University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early study tests whether adding aluminum chloride hexahydrate, a drug that stops bleeding, to standard 5-fluorouracil cream works better for actinic keratoses—rough, scaly spots from sun damage that can turn into skin cancer. About 32 adults will apply one of two creams to their scalp or forearms for a week. Researchers will count spots and check redness before, right after, and 8 weeks later to compare results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 5% 5-fluorouracil cream with or without 15% aluminum chloride hexahydrate
What this could lead to: If it works, this could point toward a more effective topical treatment for actinic keratoses, reducing the risk of skin cancer.
What could go wrong: This is a very early Phase 1 study with only 32 people, so results may not apply widely. Adding aluminum chloride could also cause more skin irritation without extra benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

actinic keratosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTINIC KERATOSES

Contacts and locations

Locations

West Virginia University
RECRUITING

Morgantown, West Virginia, 26505, United States

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