Could a bleeding stopper boost skin spot treatment?
NCT ID NCT07401277
First seen Feb 11, 2026 · Last updated Jun 19, 2026 · Updated 16 times
Summary
This early study tests whether adding aluminum chloride, a drug that stops bleeding, to a standard 5-fluorouracil cream works better for treating actinic keratoses—rough, scaly spots from sun exposure that can turn into skin cancer. Thirty-two adults with these spots on their scalp or forearms will apply either the standard cream or the combination cream for one week. Doctors will count the spots and check skin redness before treatment, right after, and again eight weeks later to see if the combination helps clear more spots.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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West Virginia University
RECRUITINGMorgantown, West Virginia, 26505, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
5% 5-fluorouracil cream with or without 15% aluminum chloride hexahydrate
What this could lead to
If it works, this could lead to a more effective topical treatment for actinic keratoses, reducing the risk of skin cancer development.
What could go wrong
This is a very early Phase 1 study with only 32 people, so results may not apply to everyone. Adding aluminum chloride could also cause more skin irritation or side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.