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New shot could tame rare leukemia in adults

NCT ID NCT07222579

First seen Nov 01, 2025 · Last updated Jun 01, 2026 · Updated 22 times

Summary

This study tests a subcutaneous (under-the-skin) form of blinatumomab for adults with a rare, aggressive leukemia called CD19-positive mixed phenotype acute leukemia (MPAL). It includes three groups: newly diagnosed patients who cannot tolerate strong chemotherapy, patients in remission with leftover cancer cells, and patients whose disease has returned or not responded to prior treatment. The goal is to see if this drug can eliminate cancer cells and improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West Virginia University Cancer Institute

    RECRUITING

    Morgantown, West Virginia, 26506, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

acute biphenotypic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.