Vanderbilt-ingram Cancer Center

This study tests a procedure called cryodevitalization, which freezes and kills early-stage lung cancer cells during a standard diagnostic bronchoscopy. About 30 people with stage I or II lung cancer will take part to see if the treatment is safe and tolerable. The goal is to fin…

This study looks at whether removing as much tumor as possible with surgery before giving a special type of radiation therapy (PRRT) works better for people with advanced neuroendocrine tumors of the gut or pancreas that have spread to the liver. About 6 adults with grade 1 or 2 …

This early-phase trial tests whether combining two imaging techniques—a radioactive scan before surgery and a fluorescent dye during surgery—can help surgeons find and remove head and neck cancer more completely. About 40 adults with head and neck cancer will receive both imaging…

This study follows 2,100 people of all ages who have had sarcoma, a type of cancer, to see how the disease and its treatments affect them over time. Researchers will review medical records and ask participants about their health and lifestyle. The goal is to learn what factors in…

This study collects blood, urine, sputum, and lung tissue from 4,000 adults at high risk for lung cancer. Researchers analyze these samples to find DNA changes and other markers that could signal cancer early. The goal is to better understand how lung cancer develops and to creat…

This study is building a registry of 10,000 adults interested in cancer genetics research. Participants fill out a consent form and questionnaires every two years, and can learn about other studies they may qualify for. There is no cost, and enrollment is available online or by m…

This study compares two ways of taking tissue samples from lung cancer patients to see which method gives better material for genetic testing. About 250 adults with suspected lung cancer will be randomly assigned to receive either a standard needle biopsy or a newer freezing tech…

This study follows 900 children who had retinoblastoma (an eye cancer) and their family members over time. Researchers collect vision tests, saliva and tissue samples, and questionnaires to understand long-term health outcomes, genetic risks, and which treatments work best. The g…

This study is testing a new way to predict whether a suspicious spot on the lung (called a pulmonary nodule) is cancer or not. Researchers will combine a blood test and a special CT scan analysis to see if it can help doctors make better decisions. About 100 adults with medium-ri…

This study collects and stores tissue samples from 3,000 people with melanoma to learn about the biological changes that happen as the disease starts and grows. The goal is to help doctors and patients choose the best treatment based on each tumor's unique features. Participants …