Vanderbilt-ingram Cancer Center

This study tests whether combining two drugs, rigosertib and pembrolizumab, can shrink tumors in people with advanced melanoma that no longer responds to standard immunotherapy. The trial enrolls about 7 adults whose melanoma has spread or cannot be surgically removed. The goal i…

This study is testing a combined biomarker model (CBM) that uses a blood test and CT scan features to better classify lung nodules as benign or cancerous. Researchers will follow 103 adults with intermediate-risk nodules to see if the model can reduce unnecessary invasive procedu…

This study tests whether an artificial intelligence (AI) tool called the Virtual Nodule Clinic can help doctors better manage lung nodules that are not clearly cancerous or benign. The AI analyzes CT scans and patient information to estimate the risk of cancer. The goal is to see…

The IMPACT Study is testing two web-based tools—GeneSHARE and LivingLabReport—to help people with inherited cancer gene variants share their genetic test results with family members and follow cancer screening guidelines. The study involves 720 adults with certain inherited cance…

This study follows 45 current or former smokers who are uninsured and have a heavy smoking history. Researchers collect samples like sputum, blood, and urine, along with CT scans, to look for early signs of lung cancer. The goal is to find better ways to detect lung cancer early …