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New drug shows promise for rare breast cancer type in early trial

NCT ID NCT05919108

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 34 times

Summary

This study tests a drug called neratinib, which blocks a protein that helps cancer cells grow. It is given before usual treatment to 30 people with stage I-III HER2-mutated lobular breast cancer. The goal is to see if it works better than standard hormone therapy at shrinking tumors and improving outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor College of Medicine

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact

  • Emory University/ Winship Cancer Institute

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

  • University of Pittsburgh Medical Center

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

  • University of Texas, Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

    Contact Email: •••••@•••••

    Contact

  • Vanderbilt University/Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

breast cancer Carcinoma, Lobular invasive lobular breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.