Uppsala University

This study compares two surgeries for thumb base arthritis: total joint replacement (using a new prosthesis) and trapeziectomy (removing a small bone). About 84 adults aged 40-80 will be randomly assigned to one surgery. Researchers will measure grip strength, pain, and costs ove…

This study tests whether extra dental support for head and neck cancer survivors can prevent or reduce late side effects like tooth loss, jaw stiffness, and cavities. About 300 adults who finished cancer treatment will receive an oral care program every three months for three yea…

This study tests whether giving two strong medications one after the other can safely control relapsing-remitting multiple sclerosis (MS) in its early stages. Sixty adults aged 18-50 with active MS will receive rituximab infusions followed by cladribine tablets, then be monitored…

This study compares three online treatments for people with clinical burnout who are on sick leave or struggling at work. 210 adults in Sweden will receive either Acceptance and Commitment Therapy (ACT), a recuperation-focused program, or ACT plus extra work support. The goal is …

This study looks at a new way to measure pain in newborns after surgery using a skin monitor. Since babies can't tell us they're in pain, doctors currently use checklists and vital signs. The skin monitor tracks stress signals continuously and may be more accurate. About 100 babi…

This study tests whether helping caregivers manage stress and learn positive parenting skills can improve the emotional and behavioral health of children in a Tanzanian refugee camp. About 324 families (around 648 children aged 7-10) will be randomly assigned to receive usual car…

This study looks at 25,000 adult ICU patients in Sweden to find out which genes and molecules make some people more likely to get very sick from infections, sepsis, or organ failure. Participants give blood samples at the hospital and again a few months later. The goal is to buil…