University Of Erlangen-nürnberg Medical School

This study is testing a procedure called renal denervation to see if it can safely lower blood pressure in people with treatment-resistant hypertension who are on hemodialysis for end-stage kidney disease. The procedure uses ultrasound to calm overactive nerves in the kidneys. Th…

This study tests whether giving less radiation after surgery for head and neck cancer can reduce long-term side effects, like trouble swallowing, without increasing the chance of cancer coming back. About 508 adults with certain types of head and neck cancer will be randomly assi…

This study looks at two different exercise programs—flexi band resistance training and whole-body electrical muscle stimulation—to see which better helps cancer patients maintain muscle strength, reduce inflammation, and improve quality of life during treatment. About 100 adults …

This study is creating a database of 100 people with advanced salivary gland cancer who receive standard radiation and chemotherapy together after surgery. Researchers will track survival, cancer return, and side effects to learn how well this treatment works in real-world settin…

This study is creating a nationwide registry and biobank for children and teens diagnosed with rare blood cancers called myeloproliferative neoplasms (MPNs). The goal is to collect medical data and blood samples from 500 participants to better understand how these diseases behave…

This study tests whether dapagliflozin, a diabetes drug, can improve kidney structure and blood flow in people with reduced kidney function one year after a kidney transplant. About 48 participants will be randomly assigned to take dapagliflozin or not, and researchers will exami…

This study tests a new, non-invasive ultrasound method to look at blood flow and tiny filters in the kidneys of children aged 1 month to 6 years who have congenital kidney or urinary tract defects. The goal is to see if this technique can provide detailed images without the need …

This study tests a new, high-resolution ultrasound technique to find early signs of kidney damage in children and teens who have been treated for acute lymphoblastic leukemia (ALL). About 30 survivors will be scanned using microbubble contrast to see tiny blood vessels in the kid…

This study tests whether 20 sessions of balance challenges on a special stationary bike can improve real-world cycling skills in adults aged 65 and older. Participants will be randomly assigned to training or a control group, and their cycling ability will be measured on a test c…

This study looks at immune markers in tumor tissue, saliva, stool, and blood from 250 patients with head and neck cancers who cannot receive the standard chemotherapy drug cisplatin. Instead, they will receive chemoradiotherapy with docetaxel. The goal is to find out which immune…

This study tests two new imaging methods—ultrasound localization microscopy and multispectral optoacoustic tomography—to check the health of kidney transplants without needing a biopsy. Ten adult kidney transplant patients who already need a biopsy will be scanned to see if these…

This study is for people with certain advanced cancers (like lung, head and neck, or esophageal cancer) who are already receiving immunotherapy. Researchers want to see if adding radiation therapy improves outcomes and, more importantly, if changes in immune cells in the blood ca…

This study is for men with prostate cancer who are getting a type of radiation called brachytherapy. Researchers want to see how the immune system changes during treatment. They will take blood and tissue samples before, during, and after the procedure. The goal is to learn more,…

This study uses a special, non-invasive eye scan called OCTA to look at tiny blood vessels in the retina. Researchers want to see if these scans can reliably show differences between people with cardiovascular disease (like high blood pressure or diabetes) and healthy volunteers.…

This study looks at the immune system in people with salivary gland tumors. Researchers will collect tumor tissue and blood samples from 300 participants to find immune markers that might predict how the disease will progress. The goal is to better understand these rare cancers a…

This study aims to test a new, non-invasive ultrasound method to see and measure the tiny blood vessels in the kidneys of adults with proteinuria (protein in urine) or active urinary sediment. About 30 participants who already need a kidney biopsy will also get this special ultra…