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Could a new ultrasound replace radiation scans for Kids' kidney defects?

NCT ID NCT06921733

Diagnosis Sponsor: University of Erlangen-Nürnberg Medical School Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new ultrasound technique that uses a contrast dye and special computer processing to create detailed images of blood flow and tiny blood vessels in the kidneys. It will involve 20 children aged 1 month to 6 years with congenital kidney and urinary tract abnormalities. The goal is to see if this non-invasive method can provide useful information without the need for radiation-based scans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Contrast enhanced ultrasound imaging (CEUS) with Ultrasound Localization Microscopy (ULM)
What this could lead to
If successful, this could lead to a safer, non-invasive way to assess kidney damage in children with CAKUT, reducing the need for scans that use radiation.
What could go wrong
This is a very small, early study (20 participants) focused on testing the imaging method, not on treatment. It may not prove that the technique works better than current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

One study population. Anticipated approx. n=20 children with above mentioned inclusion criteria with congenital anomalies of the kidney and urinary tract and inclusion criteria for MAG3 scintigraphy

Ages

0 months to 6 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Minimum Age 1 Month Maximum Age 6 Years Indication for MAG3 Scintigraphy of the Kidney Congenital Anomalies of the Kidney and Urinary Tract Obstruction Diagnosis Availability of the qualified examiner Consent of the parents/legal guardians Exclusion Criteria: Lack of consent of at least one parent

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Conditions

The condition(s) this trial relates to.

congenital anomalies of kidney and urinary tract 2 congenital anomaly of kidney and urinary tract congenital hydronephrosis lower urinary tract obstruction, congenital Multicystic renal dysplasia, bilateral

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Congenital anomalies of kidney and urinary tract Hydronephrosis congenital Lower urinary tract obstruction, congenital Ureteropelvic junction obstruction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • FAU Erlangen-Nuernberg,

    RECRUITING

    Erlangen, Bavaria, 91054, Germany

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