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MRI may spare babies radiation in kidney blockage diagnosis

NCT ID NCT05498532

Diagnosis Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether functional MRI can accurately measure kidney function in children with pyelo-ureteral junction syndrome, a common urinary blockage. Researchers compared MRI results to the standard scintigraphy scan in 270 children aged 0-17. The goal was to see if MRI could replace scintigraphy, avoiding radiation exposure, especially in infants.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Functional MRI with gadolinium contrast
What this could lead to
If successful, functional MRI could replace scintigraphy for measuring kidney function in young children, avoiding radiation exposure.
What could go wrong
This is a completed observational study, not a treatment trial. MRI may overestimate results and has limited ability to detect certain blood vessels, so it may not fully replace scintigraphy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

270 people

The number who actually took part.

Started

Sep 2022

Finished

Dec 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Children between 0 and 17 years old followed for pyelo-ureteral junction syndrome in the Children hospital of Nancy.

Ages

1 day to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * children between 0 and 17 years old * followed for pyelo-ureteral junction syndrome Exclusion Criteria: * none

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Conditions

The condition(s) this trial relates to.

bilateral multicystic dysplastic kidney congenital anomalies of kidney and urinary tract 2 stricture or kinking of ureter

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stricture of pelviureteric juncture

Contacts and locations

Locations

  • CHRU Nancy

    Vandœuvre-lès-Nancy, Lorraine, 54 511, France

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