University Hospital Tuebingen

This study tested whether a drug called bromocriptine, which boosts dopamine in the brain, can help people with obesity lose weight. The key twist: the drug's effect may depend on a person's genetic makeup, specifically a gene called FTO. 120 obese adults were given either bromoc…

This pilot study tested whether whole-body electromyostimulation (WB-EMS) training can improve blood sugar control in 66 sedentary adults aged 40-65 with prediabetes. Participants were assigned to WB-EMS or control groups, and researchers measured changes in HbA1c and other healt…

This study tested a cell-free DNA blood test to screen for trisomy 21, 18, 13 and 22q11.2 deletion in over 1,100 pregnant women during the first trimester. The goal was to see how accurate the test is compared to standard combined screening. Researchers measured how often the tes…

This small pilot study tested whether an ice plant cream could prevent hand-foot syndrome (pain, redness, peeling on hands and feet) in 15 breast cancer patients receiving doxorubicin or docetaxel chemotherapy. The main goal was to see if a larger study is possible, not to prove …

This study tested whether a 7-day supervised fast (max 350 calories per day) could reduce muscle and joint pain in 54 breast cancer patients taking aromatase inhibitors. The goal was to see if fasting is feasible and improves physical well-being and quality of life. Researchers a…

This study tested whether combining intense arm training with electrical muscle stimulation and brain stimulation could improve arm function in 20 chronic stroke survivors who had severe hand paralysis for more than 6 months. Participants received both types of brain stimulation …

This study looked at whether using a special numbing technique (tumescent local anesthesia) during breast cancer surgery leads to less pain afterward compared to standard general anesthesia. 349 women who had breast cancer surgery took part. The goal was to see if this approach c…

This study tested a non-invasive brain stimulation technique called theta burst stimulation (TBS) for people with major depression. 238 adults who had not responded well to at least one antidepressant received either real TBS or a sham (fake) version, added to their usual treatme…

This study tested a digital aftercare program for 60 children and teens leaving psychiatric hospital care. The program used regular video calls and a secure smartphone messenger to connect patients, parents, and teachers with their hospital therapist. The goal was to ease the ret…

This study tested whether a newer, more targeted type of deep brain stimulation (called directional steering) could improve Parkinson's symptoms better than the standard method. Twenty people with Parkinson's disease took part, and each tried both stimulation types in a random or…

This study looked at 270 women with early-stage, hormone-receptor-positive, HER2-negative breast cancer. Researchers used the OncotypeDX test to see how its recurrence score influenced whether doctors recommended chemotherapy. They also checked if the score was linked to cancer c…

This study looked at whether using a special ultrasound ruler during breast-conserving surgery helps surgeons remove all cancer the first time. Researchers reviewed records from 273 patients who had this ultrasound-guided surgery. The goal was to see if it lowered the rate of inc…

This completed study tested whether giving the hunger hormone ghrelin can increase motivation and change energy use in people with major depressive disorder. 24 participants received either ghrelin or a placebo injection and then performed a task where they pressed buttons to ear…

This study tested whether giving the hunger hormone ghrelin can increase dopamine release and motivation to work for rewards. Researchers used brain scans and effort tasks in 26 people (healthy volunteers and those with depression). The goal is to understand if boosting ghrelin c…

This study measured muscle activity in surgeons performing hysterectomies with robotic assistance versus conventional laparoscopy. The goal was to see which method causes less physical strain, potentially reducing work-related injuries. Four trained surgeons participated, and the…

This study tested whether artificial intelligence (AI) can automatically detect endometriosis lesions during laparoscopic surgery. Researchers used video recordings from 26 patients to train and validate an AI model. The goal was to help surgeons identify diseased tissue more acc…

This study looked at 78 women having hysterectomy or related surgery to compare robotic-assisted laparoscopy with conventional laparoscopy. The main goal was to see how long each type of surgery takes. Researchers also tracked time under anesthesia, blood loss, and other details …

This study looked at how much physical and mental stress surgeons experience during robot-assisted surgery compared to traditional laparoscopic surgery. Five trained surgeons were monitored with muscle sensors, heart rate monitors, and video recordings during routine procedures. …

This study asked over 2,600 people, including healthcare workers and the general public, about their personal preferences for how to give birth (vaginal or cesarean). Researchers also tested whether giving extra information about things like pelvic floor health or epidurals would…