New blood test could spot fetal chromosomal issues earlier and more accurately
NCT ID NCT03375359
First seen Jan 31, 2026 · Last updated Jun 20, 2026 · Updated 17 times
Summary
This study tested a cell-free DNA blood test to screen for trisomy 21, 18, 13 and 22q11.2 deletion in over 1,100 pregnant women during the first trimester. The goal was to see how accurate the test is compared to standard combined screening. Researchers measured how often the test gave a positive result, a false positive, or no result at all.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University Hospital Tuebingen, Department of Women's Health
Tübingen, 72076, Germany
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could improve early detection of chromosomal abnormalities in pregnancy, reducing false positives and unnecessary invasive tests.
What could go wrong
This is a completed diagnostic accuracy study, not a treatment trial. Results may not apply to all populations or screening settings.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.