New combo therapy shows promise for stroke patients with paralyzed arms
NCT ID NCT03947645
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether combining intense arm training with electrical muscle stimulation and brain stimulation could improve arm function in 20 chronic stroke survivors who had severe hand paralysis for more than 6 months. Participants received both types of brain stimulation in random order. The goal was to see if this approach could help them regain some movement and use of their affected arm.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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May 2019
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Written informed consent * Chronic stage of stroke (\> 6 months) * No active finger extension/hand opening of the paretic side Exclusion Criteria: * Pregnancy * Epilepsy * Metal implants * Pacemaker
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Tübingen
Tübingen, Baden-Wurttemberg, 72076, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A wearable ankle robot may boost walking recovery after stroke
- Virtual reality rehab aims to bring stroke therapy home
- Which balance training works better after stroke? a trial puts two methods to the test
- Could a cuff and a tingle restore leg strength after stroke?
- Can gentle electrical pulses reawaken hand movement after stroke?
- Can foot sensation predict balance problems in stroke survivors?