University Hospital, Angers

This study looks back at 90 children treated for pilonidal sinus disease to see which surgical technique works best. The goal is to find the method that leads to the fastest healing and lowest chance of the problem coming back. Results will help doctors choose the best surgery fo…

This study looks at different surgical techniques for treating Hirschsprung disease, a rare condition where part of the colon lacks nerve cells, causing bowel blockages. Researchers will compare a newer single-port laparoscopic method with traditional approaches in 70 children un…

This early study tests whether high-dose vitamin B3 (nicotinamide) can help preserve or improve vision in people with Leber's hereditary optic neuropathy (LHON), a rare genetic disease that causes sudden vision loss. Researchers will give 13 participants 2 grams of vitamin B3 dai…

This study looks at whether blood clots in the lungs (pulmonary embolism) are often missed in people hospitalized with acute heart failure. About 740 patients across multiple hospitals will take part. In half the hospitals, doctors will follow their usual approach; in the other h…

This study tests a simple 10-item checklist that parents can use during a video call to help doctors figure out if a child's belly pain is appendicitis. About 1,500 children aged 3 to 16 with stomach pain will try the checklist with a medical student, then get standard care. The …

This study tests whether a short, personalized talk with an advanced practice nurse in the pediatric emergency room can help parents of infants (0-6 months) follow safe sleeping guidelines. Researchers will compare how many babies are placed safely on their backs before and after…

This study looks at whether people with a moderate-risk blood clot in the lungs can be safely treated at home instead of staying in the hospital. About 568 adults will be randomly assigned to either go home early or receive standard hospital care. The goal is to see if home treat…

This study looks at two methods to control pain after hindfoot surgery: a single nerve block injection versus a small tube (catheter) that delivers numbing medicine continuously for days. The goal is to see which approach reduces pain, cuts down on opioid use, and helps people re…

This study looks at how Huntington's disease impacts autobiographical memory—the ability to recall personal experiences and imagine future events. Researchers will use eye-tracking and neuropsychological tests in 80 participants (patients and healthy controls) to find markers of …

This study tests two strategies for removing a temporary brain drain (external ventricular drain) in patients with bleeding around the brain. One method clamps the drain directly when ready, the other raises it gradually. The goal is to see which approach reduces the time the dra…

Human seminal plasma allergy is a rare condition causing pain and inflammation after unprotected sex, but its impact on quality of life is poorly understood. This study will enroll 20 women treated at Angers University Hospital to compare standard quality-of-life questionnaires a…

This study looks at children with spinal dysraphism, a birth defect where the spine doesn't close properly. The goal is to better understand bladder and bowel problems in these children, especially those with less obvious forms. By studying 210 children treated at one hospital ov…

This study looks at how different levels of breathing support (PEEP) affect blood flow congestion in the veins of patients with acute respiratory distress syndrome (ARDS). Researchers will use ultrasound to grade congestion in the liver, kidney, and portal veins as absent, modera…

This study looks at whether the force of mechanical ventilation used in acute respiratory distress syndrome (ARDS) can cause brain injury. Researchers will measure a brain-damage marker called S100B in 150 adults and test their memory and thinking skills 3 and 12 months later. Th…

This study looks at children who had surgery for a blocked duodenum (the first part of the small intestine) at birth. The goal is to find out how often bile duct and pancreas problems happen after that surgery. Researchers will review medical records from the past 20 years across…

This study looks at how certain thinking skills, called executive functions, are linked to suicidal thoughts and actions in teenagers. Researchers will test 100 adolescents aged 11 to 16 who are in the hospital for suicidal behavior. The goal is to find patterns that could lead t…