Hidden clots in heart failure? new study tests routine screening
NCT ID NCT07499661
First seen Mar 30, 2026 · Last updated Jun 20, 2026 · Updated 18 times
Summary
This study looks at whether blood clots in the lungs (pulmonary embolism) are often missed in people hospitalized with acute heart failure. About 740 patients across multiple hospitals will take part. In half the hospitals, doctors will follow their usual approach; in the other half, they will systematically test every patient for a clot using a standard diagnostic checklist. The goal is to see if routine testing leads to more diagnoses and better outcomes.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Agen Hospital, Emergency department
Agen, 47923, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Angers University Hospital, Emergency Department
Angers, 49000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Brest University Hospital (site Cavale Blanche), Cardiology Department
Brest, 29200, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cholet Hospital, Emergency Department
Cholet, 49300, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clermont-Ferrand University Hospital, Emergency Department
Clermont-Ferrand, 63000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Grenoble Alpes University Hospital, Adult Emergency Department
La Tronche, 38700, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lyon University Hospital (site Edouard Herriot), Emergency Department
Lyon, 69003, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Poitiers University Hospital, Emergency Department
Poitiers, 86000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Toulouse University Hospital, Emergency Department
Toulouse, 31000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tours University Hospital (site Trousseau), Adult Emergency Department
Chambray-lès-Tours, 37170, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Systematic diagnostic algorithm for pulmonary embolism (including Geneva score, D-dimer testing, and imaging)
What this could lead to
If successful, this could show that routine screening for blood clots in the lungs is worthwhile for all patients hospitalized with acute heart failure, leading to earlier treatment and fewer complications.
What could go wrong
This is a pragmatic trial testing a diagnostic strategy, not a new treatment. The expected increase in detection is modest (from 1% to 5%), and it may not translate into better survival or fewer hospital readmissions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.