Universitaire Ziekenhuizen Ku Leuven

This study compares the safety of the drug flecainide to standard rhythm-control medications (sotalol or amiodarone) in about 988 adults with atrial fibrillation and stable coronary artery disease. Participants will be randomly assigned to one treatment and followed for at least …

This study tests whether adding two targeted drugs (zanidatamab and tislelizumab) to standard chemotherapy can completely eliminate HER2-positive gastroesophageal cancer before surgery. About 29 adults with operable, locally advanced cancer will receive the combination before and…

This study tests whether a herbal medicine called STW 5-II can reduce gut inflammation and ease symptoms like bloating and stomach pain in adults with functional dyspepsia. About 100 participants will take either STW 5-II or a placebo for 8 weeks, then have a gut tissue sample ta…

This study tests a step-by-step rehabilitation program for adults having back surgery for leg pain caused by a pinched nerve. The program includes exercises before and after surgery, early movement, and guidance on returning to work. Researchers want to see if this approach helps…

This study looks at gut changes in people with untreated Parkinson's disease compared to healthy volunteers. Researchers will measure gut permeability, microbiome, and transit time to see how the gut is affected early in the disease. No treatment is tested; the goal is to learn m…

This study tests whether giving low-risk skin cancer patients a personalized discharge letter after screening helps them feel more reassured and understand their risk better. About 150 patients will be split into groups: standard care, a generic letter, or a personalized letter c…

This study looks at young adults aged 18-35 with hip impingement, a condition that can lead to early arthritis. The goal is to create simple, clinic-friendly tests to help doctors decide who should continue with non-surgical care and who needs surgery sooner. By using movement an…

This study looks at whether a harmless thermal camera can help doctors see early signs of infection or slow healing after skin surgery. About 120 adults having skin lesions removed will have their wounds photographed with the camera. The goal is to find problems sooner so doctors…

This study follows 100 people who receive the 5C MEDic knee replacement system to see how safe and effective it is over 5 years. Researchers will track how many need a second surgery and how their daily life and pain change. The goal is to confirm the implant works well and spot …

This study looks at how knee braces and a surgery called high tibial osteotomy (HTO) change the bone and cartilage in people with knee osteoarthritis and misaligned legs. Researchers will use advanced scans and computer models to measure bone strength and how weight shifts in the…