Union Hospital, Tongji Medical College, Huazhong University Of Science And Technology

This early-phase trial is testing a new gene therapy called ESO-T01 for people with relapsed or refractory multiple myeloma, a blood cancer that has stopped responding to standard treatments. ESO-T01 is given as an injection and works by instructing the body's own cells to become…

This trial tests whether taking a daily low dose of colchicine, an anti-inflammatory drug, can reduce the risk of heart attacks, strokes, and other heart problems in Chinese patients who have had a stent placed for coronary heart disease. Researchers will compare two different do…

This study tests whether fecal microbiota transplantation (FMT) — transferring healthy donor stool into the gut — can lower the risk of death in ventilated ICU patients with multidrug-resistant lung infections. The idea is that restoring gut bacteria may help fight lung infection…

This study planned to test a new CAR-T cell therapy called LCAR-AIO in adults with relapsed or treatment-resistant neurological autoimmune diseases, including multiple sclerosis and myasthenia gravis. The goal was to check safety and find the right dose. However, the trial was wi…

This Phase 3 trial tests whether a short course of radiotherapy followed by the immunotherapy drug camrelizumab plus chemotherapy works better than standard long-term chemoradiation for locally advanced rectal cancer. About 230 patients will be randomly assigned to one of the two…

This study aims to see if growing a patient's tumor cells in the lab (called organoids) can help doctors choose the most effective first-line chemotherapy for advanced leiomyosarcoma, a rare cancer of smooth muscle. About 50 adults aged 18-75 who have not yet received systemic tr…

This early-stage trial tests a new treatment called RD06-04, a CAR-T cell therapy, in 12 people with moderate to severe lupus. The therapy aims to target and reset immune cells that attack the body. The main goal is to check safety and find the right dose, with a close watch for …

Researchers are building deep learning models that analyze digital images of kidney biopsy tissue to classify kidney diseases such as IgA nephropathy and membranous nephropathy. The study uses pathology images and clinical data from thousands of patients who had kidney biopsies a…

This trial tests whether an AI tool called DeepBMD can identify people at high risk for osteoporosis using CT scans they've already had for other reasons. Researchers will compare the AI's findings with the standard bone density test (DXA) to see if it's accurate. If it works, th…

This trial is testing an experimental imaging agent called [68Ga]Ga-ELI411, which is designed to bind to a protein (FAP) found in many solid tumors. The study will involve 18 adults with confirmed solid tumors who are already scheduled for a standard FDG-PET scan. Participants wi…