Tufts Medical Center
Clinical trials sponsored by Tufts Medical Center, explained in plain language.
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New combo therapy for tough prostate cancer shows promise in early trial
Disease control CompletedThis early-phase study tested a combination of two treatments—a chemotherapy drug (docetaxel) given in smaller, split doses and a targeted radiation therapy (radium-223)—in 43 men with advanced prostate cancer that no longer responds to hormone therapy. The main goal was to find …
Phase: PHASE1 • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated May 26, 2026 03:06 UTC
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Texts and talks trim waistlines in housing study
Disease control CompletedThis study tested if a 1-year text messaging program, with or without monthly calls from a community health worker, could help 316 public housing residents in Boston lose weight. Participants were split into three groups: text messages only, texts plus phone coaching, or a contro…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Can a Pre-Pregnancy diet and exercise program break the obesity cycle?
Prevention CompletedThis study tested whether starting a lifestyle program before pregnancy can improve health for both mother and baby. Researchers enrolled 99 women who had a previous full-term pregnancy and were planning another within two years. The program focused on diet and exercise to reduce…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Prevention
Last updated May 19, 2026 11:59 UTC
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Can walking trails and phone coaching get low-income residents moving?
Knowledge-focused CompletedThis study looked at whether adding walking trails, maps, and a phone-based coaching program helps people living in public housing become more physically active. Over 500 residents from 12 Boston housing developments took part. The goal was to see if these changes increase modera…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Video decision aids help seniors and dementia patients plan End-of-Life care
Knowledge-focused CompletedThis study tested whether showing videos about advance care planning helps elderly patients (65+) and those with dementia make better decisions about their medical care. Over 11,000 hospitalized patients and 600 caregivers took part at two major hospitals. The goal was to see if …
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC
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Gut check: can Mind-Body exercise soothe arthritis?
Knowledge-focused CompletedThis study looked at how mind-body exercise (like yoga or tai chi) compares to a wellness education program in changing gut bacteria in people with osteoarthritis. 72 adults aged 55 and older with knee or hip arthritis took part. The goal was to gather information for a larger fu…
Phase: NA • Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:11 UTC
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Ultrasound may replace X-Ray for muscle checks in heart failure
Knowledge-focused CompletedThis study tested whether a portable ultrasound device can accurately measure muscle loss in people with heart failure, compared to the standard X-ray method. Researchers enrolled 48 participants, including healthy volunteers and heart failure patients. The goal was to see if ult…
Sponsor: Tufts Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:10 UTC