Tufts Medical Center

This study tests whether taking a weekly dose of vitamin D, adjusted to reach a target blood level, can help control blood sugar in 100 adults aged 30-74 with prediabetes. Participants are randomly assigned to receive either vitamin D or a placebo for about 18 months. The main go…

This study tests whether using lung ultrasound to guide breathing support can help infants with respiratory failure leave the NICU sooner. About 64 newborns will be randomly assigned to either ultrasound-guided care or standard care. The goal is to see if this approach reduces ti…

This study aims to learn which rheumatoid arthritis (RA) medication works best for each individual patient by using a personalized N-of-1 trial design. Participants will try up to four FDA-approved RA drugs in a random order and report their symptoms and quality of life through q…

This study compares a new method using a green dye (ICG) and a special camera to the standard blue dye for finding lymph nodes in early-stage vulvar cancer. Ten adults with early-stage vulvar cancer will receive both dyes so doctors can see if the green dye works just as well. Th…