The First Hospital Of Jilin University

This study tests a new type of CAR-T cell therapy, boosted with a protein called IL-15, in people with multiple myeloma or plasma cell leukemia that has come back or not responded to treatment. The goal is to see if these enhanced immune cells can shrink or eliminate the cancer. …

This study tests whether adding daphnetin capsules to standard chemotherapy and targeted therapy can help control advanced ovarian cancer (stage III-IV) after initial surgery. About 98 participants will receive the treatment and be monitored for side effects and cancer progressio…

This study tests whether combining budesonide and ambrisentan can reduce protein in the urine and slow kidney function decline in people with IgA nephropathy, a chronic kidney disease. About 129 adults with mild to moderate kidney damage will receive both drugs for 36 weeks. The …

This study tests whether adding an experimental drug called CapsuleX to the chemo drug cisplatin can shrink tumors in people with ovarian cancer that no longer responds to platinum-based treatments. About 40 adults with recurrent ovarian, fallopian tube, or primary peritoneal can…

This study is for people with advanced colorectal cancer that didn't respond to or caused side effects from first-line treatment. It tests a combination of chemotherapy drugs (Levoleucovorin, 5-FU, and liposomal irinotecan) with or without targeted therapies (cetuximab or bevaciz…

This study tests if a newer surgery (Turnbull-Cutait) helps people with low rectal cancer avoid a permanent stoma longer than the standard surgery. About 520 adults will be randomly assigned to one of the two surgeries and followed for three years. The goal is to see which approa…

This study tests whether an artificial intelligence (AI) smartphone app can help people with type 2 diabetes control their blood sugar better than standard doctor visits. About 400 adults will use the app to track their food, exercise, and glucose, receiving personalized advice o…

This study tests whether giving the blood-thinning drug tirofiban soon after standard clot-busting treatment helps people recover better from a stroke. About 1,084 adults who had a moderate stroke will receive either tirofiban or a placebo within 6 hours of their first treatment.…

This study tests whether a liquid called Paiteling can clear persistent high-risk HPV infections in the cervix. It involves 115 women aged 25 to 65 who have had the same high-risk HPV type for at least two years. The main goal is to see if the infection turns negative 12 months a…

This study is for people with a rare type of skin cancer called mucosal melanoma that has been completely removed by surgery and tests positive for PD-L1. The trial compares adding the immunotherapy drug sintilimab to standard chemotherapy versus chemotherapy alone to see if the …

This study looks at whether lowering the amount of liquid food given through a feeding tube before turning a patient onto their stomach (prone position) can reduce stomach problems in adults with severe lung failure (ARDS) on breathing machines. About 259 ICU patients will be ran…

This study is for people with mid-to-low rectal cancer that has high-risk features. It compares two treatment plans: short-course radiation followed by chemotherapy plus an immunotherapy drug (toripalimab), with or without an additional anti-angiogenic drug (surufatinib). The goa…

This study looks at whether a special ultrasound technique, combined with liver stiffness and platelet count, can accurately detect high-risk varices (enlarged veins) in the stomach and esophagus of people with liver cirrhosis. About 380 adults with cirrhosis will be tested. The …

This study aims to find out why some people with ureteral stones develop inflammatory polyps (growths) in the tube that carries urine from the kidney to the bladder. Researchers will look at past patient records and then test their predictions on 300 new adult patients. The goal …

This study follows 900 lung cancer surgery patients for 30 days after their operation. Researchers collect medical data to find which factors increase the risk of developing blood clots in the legs (deep vein thrombosis). They will use machine learning to create a tool that predi…

This study looks at tiny particles called extracellular vesicles in the blood of people with brain aneurysms. Researchers want to see if the proteins in these particles differ depending on where in the body the blood is taken from. They hope to find markers that could help diagno…