The Affiliated Nanjing Drum Tower Hospital Of Nanjing University Medical School

This study tests a combination of two drugs (carilizumab and apatinib mesylate) plus radiation therapy as a first treatment for advanced mucosal melanoma, a rare and aggressive skin cancer. The goal is to see if this approach can control the disease longer and improve survival. A…

This study tests whether a woman's own immune cells, turned into special decidual-like NK cells in a lab and then placed back into the uterus, can improve pregnancy success. It is for women who have had repeated miscarriages or unexplained infertility linked to abnormal uterine N…

This study compares two procedures for removing small rectal neuroendocrine tumors (less than 1 cm). The goal is to see if a newer, modified snare technique is as effective as the standard method but faster and with fewer complications. About 118 adults with these tumors will tak…

This study tests whether starting a type of dialysis (CVVHDF) immediately after a blood-filtering treatment can help people who have swallowed a large amount of the herbicide diquat. Diquat poisoning can cause severe organ damage and death. The trial will include 24 adults with v…

This study tests whether a newer device called a flow diverter works better than the standard stent-assisted coiling for treating brain aneurysms in a key location. About 140 adults with unruptured aneurysms will be randomly assigned to one of the two treatments. The main goal is…

This study compares two ways of starting a type of dialysis (CVVHDF) in people who have swallowed a large amount of the herbicide diquat. The standard approach waits until kidney damage appears, while the accelerated approach starts dialysis right away. The goal is to see if earl…

This early study tests a new treatment called CHT105 for people with severe lupus that has not responded to standard therapies. CHT105 uses donor immune cells engineered to find and destroy the faulty immune cells driving the disease. The main goals are to check safety and see if…

This early study tests a virus-based treatment (phage therapy) for urinary tract infections caused by drug-resistant bacteria. Six adults aged 18-65 will receive the phage cocktail for 2-3 days and be followed for up to 4 weeks. The goal is to see if it safely clears the infectio…

This study tests a drug called entinostat combined with chemotherapy for people with advanced bladder cancer that has not responded to initial treatment. The goal is to see if this combination can shrink tumors or slow the disease. About 29 participants will receive the treatment…

This study tests a personalized approach for people with advanced liver cancer that cannot be removed by surgery. Researchers will analyze the tumor's metabolism (how it uses fat for energy) to assign each patient to a specific treatment combination. The goal is to see if this ta…

This study checks if a new portable mass spectrometry device can accurately measure diquat (a toxic herbicide) in human blood samples. Researchers will compare results from 60 poisoned patients against the standard lab method. The goal is to provide faster and reliable diagnosis …

This study tests whether a gentle brain stimulation technique called tDCS, combined with hand muscle electrical therapy, can improve hand function in people who had a stroke. Fifty-six participants will receive either real or fake tDCS for 20 sessions over four weeks. Researchers…

This study tests whether taking fish oil by mouth can prevent or reduce peripheral neuropathy—nerve damage causing pain, numbness, or tingling—in people with multiple myeloma receiving the chemotherapy drug bortezomib. About 200 adults starting bortezomib for the first time will …

This study checks if a new model can predict which ICU patients will get a serious, drug-resistant infection called MDRGNB. Researchers will watch 1,000 adults in the ICU to see if the model's predictions match what actually happens. The goal is to help doctors spot high-risk pat…

This study will use artificial intelligence to create a tool that predicts a person's risk of head and neck cancer. Researchers will analyze data from 3,000 adults, including medical history, lifestyle habits, and laryngoscopy images. The goal is to help doctors catch these cance…