Sunnybrook Health Sciences Centre

This trial tested whether giving antibiotics after surgically draining a perianal abscess helps prevent painful complications. Adults who needed the drainage procedure were randomly assigned to receive either standard care with antibiotics or standard care without them. The main …

This small pilot study tested whether combining physical exercise with a mild, non-invasive brain stimulation technique could help improve memory in people with mild cognitive impairment or early Alzheimer's disease. Researchers wanted to see if stimulating the brain during exerc…

This study tested if chewable Dex4 tablets work as well as the standard sugary drink for diagnosing gestational diabetes. Researchers compared the two methods in pregnant women who had already screened positive, looking at blood sugar results and side effects like nausea. The goa…

This study tested whether a new, high-resolution ultrasound technology is as good as or better than the standard MRI method for guiding prostate biopsies. It involved 804 men who needed a biopsy due to elevated PSA levels or an abnormal exam. Researchers compared how well each im…

This study tested whether a newer type of brain scan (FET-PET/MRI) could more accurately map the remaining tumor after surgery compared to the standard MRI scan. The goal was to see if this could help doctors better target radiation therapy, potentially improving treatment effect…

This large study aimed to find out if washing a surgical cut with an antiseptic or salt water solution before stitching it closed can prevent infections. Over 2,700 adults having planned abdominal or groin surgery were randomly assigned to get one of these washes or no wash at al…

This study tested whether drinking coffee after abdominal surgery helps patients' digestive systems recover faster. Researchers gave 174 patients either regular coffee, decaf coffee, or warm water three times a day after their operations. The main goal was to see if a larger futu…

This study tested whether regularly applying ice packs over surgical incisions helps people recover better after major surgery. Researchers enrolled 196 adults having chest, abdominal, or groin surgery. Half were asked to use ice packs every few hours for three days after their o…

This study tested whether giving paramedics real-time feedback about their CPR ventilation technique improves the quality of care during out-of-hospital cardiac arrests. Researchers compared ventilation quality before and after paramedics used a monitoring device that shows if th…

This study aimed to find the best dose of a drug called tranexamic acid (TXA) for patients getting hip or knee replacements. TXA helps control bleeding during surgery, which can reduce the need for blood transfusions. Researchers tested how the drug was processed in the bodies of…