Sheba Medical Center

This study follows 120 Israeli children and teens with type 1 diabetes who are starting to use the Medtronic 780G insulin pump system. Researchers want to see if the system helps them keep their blood sugar in a healthy range more often and improves their quality of life. Partici…

This study tests whether adding azithromycin to the usual antibiotic (ampicillin) improves health outcomes for newborns when a woman's water breaks early (between 34 and 37 weeks of pregnancy). About 311 women will receive either ampicillin alone or ampicillin plus azithromycin w…

This study tests a new treatment for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard therapies. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack cancer cells carrying a …

This study is testing whether a portable virtual reality (VR) headset can help diagnose and monitor traumatic brain injury (TBI), like concussions. The device shines colored lights into the eyes and uses a camera to measure how the pupils react. Researchers will compare results f…

This study tests whether the drug carbetocin works better than standard oxytocin to prevent heavy bleeding after twin deliveries. Heavy bleeding is more common with twins and can cause serious health problems. About 120 pregnant people with twins will be randomly assigned to rece…

This study compares group-based MDMA-assisted therapy to individual sessions for people diagnosed with PTSD after the events of October 7, 2023. Researchers want to see if the group approach is as safe and effective as individual therapy. Participants will receive MDMA in a contr…

This study is testing a new, non-invasive eye test called pupillometry to see if it can detect vision problems in people with pseudotumor cerebri (a condition where pressure builds up in the skull). Researchers will measure how the pupils react to colored lights in 50 patients an…

This study is testing whether temporarily opening the protective barrier around the brain (the blood-brain barrier) during spine surgery can release brain tumor markers into the blood, making them easier to detect with a simple blood test. About 20 adults having spine surgery for…

This study looks at saliva from people with Oculopharyngeal Muscular Dystrophy (OPMD) and their household members. Researchers want to see if swallowing problems affect oral health and if saliva thickness or certain chemicals can help detect the disease. About 100 participants wi…

This study looks at how different arm positions change blood pressure readings in pregnant women. About 300 participants will have their blood pressure taken with their arm at heart level, on their lap, and hanging at their side. The goal is to find out which position gives the m…

This study is testing whether a personalized health and behavior program can slow or reverse biological aging in healthy adults over 50. About 1,500 participants will be randomly assigned to either receive a custom intervention plan or just standard assessments. The goal is to se…

This study aims to understand how laser light reflects from different parts of the eye, such as the cornea and retina. Researchers will measure the reflected laser radiation at various angles and wavelengths in 20 healthy volunteers aged 18-40. The goal is to improve the safety a…