Sheba Medical Center
Clinical trials sponsored by Sheba Medical Center, explained in plain language.
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Alga extract may slow vision loss in teens with rare eye disease
Disease control Not yet recruitingThis study tests whether a powder made from a special alga can help preserve vision in teenagers with retinitis pigmentosa, a genetic eye disease that causes gradual vision loss. About 30 adolescents aged 12-18 will take the alga extract by mouth. The goal is to see if it can slo…
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 26, 2026 04:42 UTC
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Could fewer infusions tame thyroid eye disease just as well?
Disease control Not yet recruitingThis study compares a shortened 4-infusion course of the drug Teprotumumab (Tepezza) to the standard 8-infusion course in people with active thyroid eye disease (TED). The goal is to see if those who respond well early can safely stop treatment sooner with the same benefits. The …
Phase: PHASE4 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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New CAR T-Cell therapy targets Hard-to-Treat blood cancers
Disease control Not yet recruitingThis study tests a new treatment called SHB-02-CD19 for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack cancer cells. The goal is …
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Could an algae pill help people see better in the dark?
Symptom relief Not yet recruitingThis study tests whether a natural supplement made from algae can improve vision in adults with Retinitis Pigmentosa, an eye disease that causes vision loss. 41 participants will take either the supplement or a placebo for 3 months, then switch after a 6-month break. The goal is …
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Symptom relief
Last updated May 26, 2026 04:35 UTC
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Sticky patch could replace needles for facial nerve safety in surgery
Knowledge-focused Not yet recruitingThis study tests if a non-invasive, wireless patch can safely monitor facial nerve activity during parotid or facial surgery, potentially replacing standard needle-based methods. Twenty adults will have both the patch and standard monitoring during their surgery, and researchers …
Phase: NA • Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:45 UTC
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Scientists probe mitochondria to unlock depression treatment secrets
Knowledge-focused Not yet recruitingThis study looks at how S-ketamine, a fast-acting antidepressant, affects tiny energy-producing parts of cells called mitochondria in people with treatment-resistant depression. Researchers will take blood samples before, shortly after, and six weeks after treatment to see if cha…
Sponsor: Sheba Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:39 UTC