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Scientists probe mitochondria to unlock depression treatment secrets

NCT ID NCT07399756

First seen Feb 21, 2026 · Last updated May 22, 2026 · Updated 7 times

Summary

This study looks at how S-ketamine, a fast-acting antidepressant, affects tiny energy-producing parts of cells called mitochondria in people with treatment-resistant depression. Researchers will take blood samples before, shortly after, and six weeks after treatment to see if changes in mitochondrial markers can predict who will respond well. The goal is to better understand how the drug works and find simple blood tests to guide treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sheba Medical Center

    Ramat Gan, Israel, 52621, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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