Shanghai Pulmonary Hospital, Shanghai, China

This study tests an oral chemotherapy drug (paclitaxel) combined with immunotherapy given before surgery for elderly patients (ages 70-85) with non-small cell lung cancer. The goal is to see if this approach can shrink tumors and improve outcomes. About 75 participants will recei…

This study tests whether adding acetohydroxamic acid (AHA) to a short-course drug regimen can safely and effectively treat multidrug-resistant tuberculosis (MDR-TB). About 120 adults with confirmed MDR-TB will receive either AHA or a placebo alongside standard antibiotics. The go…

This study tests whether adding the targeted drug bozitinib to standard chemotherapy can shrink tumors more effectively before surgery in people with a specific genetic subtype of lung cancer (MET-altered). About 34 adults with stage IIA to IIIC non-small cell lung cancer will re…

This study tests a special care plan (CEPM) to help manage side effects like skin rash and infusion reactions in people with advanced EGFR-mutated lung cancer who are taking the drug amivantamab. About 122 Chinese adults will join to see if this plan improves their quality of lif…

This study tests a combination of a chemotherapy drug (nab-paclitaxel) and local radiation therapy for people with advanced small-cell lung cancer whose disease got worse after initial treatment. The goal is to see if this approach can control the cancer longer and with fewer sid…

This study tests whether giving a combination of three drugs (JSKN016, toripalimab, and carboplatin) before surgery can help shrink tumors in people with stage II or III non-small cell lung cancer. About 54 adults will receive the treatment before their operation. The main goal i…

This study compares two types of lung cancer surgery—segmentectomy (removing only part of a lung lobe) and lobectomy (removing an entire lobe)—for people with a specific type of early-stage lung cancer (2-3 cm tumors). About 587 adults aged 20-79 will be randomly assigned to one …

This study tests whether combining a targeted drug (furmonertinib) with local treatments like ablation or stereotactic radiation can help control early-stage non-small cell lung cancer in people who cannot have surgery or choose not to. About 45 participants with specific EGFR ge…

This study tests whether taking ensartinib (a targeted pill) after chemoradiation can help people with ALK-mutated stage III lung cancer that cannot be removed by surgery. About 45 adults who have finished chemoradiation without their cancer getting worse will be randomly assigne…

This study looks at whether a painless electrical treatment called TEAS, applied to specific points on the body before lung surgery, can prevent or reduce shoulder pain that often follows. About 216 adults having keyhole lung surgery will be randomly assigned to receive TEAS or u…

This study tests whether adding a traditional Chinese herbal formula (Huanjingjian decoction) to standard hormone therapy can improve quality of life for women with premature ovarian insufficiency (early menopause). About 276 women aged 18-39 will take either the herbal formula o…

This study tests whether a numbing medicine called bupivacaine, given directly into the chest through a tube, can reduce pain after minimally invasive lung surgery. About 249 adults having lung surgery will receive either a low or high dose of bupivacaine or a placebo. The goal i…

This study tests whether a new electromagnetic navigation system can help surgeons find small lung nodules more accurately than the standard CT-guided method. About 400 adults with a single lung nodule up to 2 cm will be randomly assigned to one of the two techniques. The goal is…

This study will test a new way to detect lung cancer early by combining CT scans with a blood test that looks for DNA changes. Researchers will study 14,300 people aged 40-74 who have been diagnosed with cancer but haven't started treatment yet. The goal is to see if this combine…