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Chest tube painkiller may ease recovery after lung surgery

NCT ID NCT07393386

Symptom relief Sponsor: Shanghai Pulmonary Hospital, Shanghai, China Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests if giving the numbing drug bupivacaine through a chest tube can reduce pain after minimally invasive lung surgery. About 249 adults having video-assisted thoracoscopic surgery will receive either a low or high dose of bupivacaine, or a placebo. The main goal is to see if it lowers pain during coughing in the first two days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If it works, this could provide a better way to manage pain after lung surgery, reducing the need for opioids and speeding up recovery.
What could go wrong
This is a single-center, early-phase trial. The results may not apply to all patients, and there is a risk of side effects from bupivacaine, such as nerve or heart issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 249 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients scheduled for elective video-assisted thoracoscopic surgery 2. Age≥18 years 3. American Society of Anesthesiologists (ASA) physical status classification I-III Exclusion Criteria: 1. Pregnancy or breastfeeding 2. History of chronic pain 3. History of alcohol or opioid dependence 4. Significant cardiopulmonary dysfunction, including heart failure or severe cardiac conduction abnormalities 5. Coexisting central nervous system disorders 6. Hepatic or renal dysfunction 7. Known hypersensitivity to local anesthetics or opioids 8. Local infection at or near the planned site of regional anesthesia, or systemic infection 9. Language impairment or difficulty in communication 10. Refusal to participate in the study or refusal to use patient-controlled analgesia 11. Concurrent participation in another clinical trial

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Conditions

The condition(s) this trial relates to.

agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Shanghai Pulmonary Hospital

    Shanghai, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.