Shanghai Pulmonary Hospital, Shanghai, China

This study tests a drug called teniposide in 15 people with advanced small cell lung cancer that has a specific gene change (c-Myc) and has stopped responding to standard treatments. The goal is to see if the drug can shrink tumors and control the disease. Participants must be in…

This study tests whether a combination of two drugs (sacituzumab tirumotecan and limertinib) can shrink locally advanced EGFR-mutant lung cancer enough to allow surgery. About 36 adults who have not had prior treatment will receive the drugs before surgery. The main goal is to se…

This study is for people with stage II or III non-small cell lung cancer who are scheduled for surgery. It tests whether giving a combination of two immunotherapy drugs (sintilimab and IBI310) plus chemotherapy before surgery can shrink tumors more effectively. The goal is to see…

This study tests whether a new drug called IBI363, combined with chemotherapy, can shrink stage III lung cancer that cannot be surgically removed. The goal is to make the cancer small enough for surgery. About 43 adults with this type of lung cancer will take part. The main focus…

This study tests whether combining the drug envolizumab with radiation therapy before surgery can shrink tumors in people with locally advanced thymic carcinoma, a rare chest cancer. About 25 adults aged 18-75 will receive the combination treatment, then have surgery to remove an…

This study compares two types of lung surgery for people with small lung cancers (≤2 cm). One surgery removes only a part of the lung lobe (segmentectomy), while the other removes the entire lobe (lobectomy). The goal is to see if the smaller surgery works just as well at prevent…

This study aims to see if synthetic PET images, created from standard CT scans using artificial intelligence, can accurately diagnose and guide treatment for lung cancer. Researchers will enroll 10,000 people with non-small cell lung cancer to compare the synthetic images with re…

This study compares a long-acting painkiller (liposomal bupivacaine) to a standard one (bupivacaine hydrochloride) for pain relief after lung surgery. About 210 adults having chest surgery will be randomly assigned to one of three groups. The goal is to see if the long-acting ver…

This study compares two medications, sugammadex and neostigmine, given at the end of lung surgery to reverse muscle relaxants. The goal is to see which drug helps patients breathe better in the first hour after surgery. 240 adults having a small part of one lung removed will take…

This study looks at whether a lab-made model of a patient's lung cancer tumor can help doctors choose the best drugs. Researchers will grow tumor-like cell clusters from patient samples and test which medicines work best. The goal is to see if these lab results match real patient…

This study is for adults in China with bronchiectasis, a lung condition that causes coughing and infections. Researchers want to find different types of the disease by looking at patients' genes and health data. The goal is to better predict how the disease will progress and choo…