Shanghai Pulmonary Hospital, Shanghai, China

This study tests whether giving a combination of two immunotherapy drugs (sintilimab and IBI310) plus chemotherapy before surgery can shrink tumors in people with stage II to III non-small cell lung cancer. About 54 participants will receive the treatment and then have surgery to…

This study tests whether a combination of two drugs (sacituzumab tirumotecan and limertinib) can shrink advanced EGFR-mutant lung cancer enough to allow surgery. About 36 adults with locally advanced, potentially resectable cancer who haven't had prior treatment will receive the …

This study compares two types of lung surgery for people with small lung cancers (≤2 cm). One surgery removes only a part of the lung lobe (segmentectomy), while the other removes the entire lobe (lobectomy). The goal is to see if the smaller surgery works just as well at prevent…

This study tests the drug teniposide in 15 people with extensive-stage small cell lung cancer that has a specific gene change (c-Myc-driven) and has stopped responding to standard treatments. The goal is to see if teniposide can shrink tumors and control the disease. Participants…

This study tests whether a new drug (IBI363) combined with chemotherapy can shrink stage III lung cancer that cannot be surgically removed, making it possible to operate. About 43 adults with this type of lung cancer will receive the treatment before surgery. The main goal is to …

This study aims to see if we can create PET-like images from a standard CT scan using artificial intelligence. If successful, it could help doctors diagnose and treat lung cancer more accurately without the need for a separate PET scan. The study will involve 10,000 people with n…

This study tests whether a newer drug, sugammadex, helps people breathe better right after lung surgery compared to an older drug, neostigmine. About 240 adults having a small part of their lung removed will be randomly assigned to receive one of the two drugs. The main goal is t…

This study compares two numbing medicines for pain after lung surgery. One is a long-acting version that may keep pain away for over 24 hours. About 210 adults having lung surgery will be randomly assigned to receive the long-acting drug, the standard drug, or no numbing block. T…

This study is observing 1500 adults in China with bronchiectasis, a lung condition that causes coughing and infections. Researchers want to find different types of the disease based on genetics and other factors. This will help doctors predict how the disease will progress and ch…

This study looks at whether a lab-grown model made from a patient's own lung cancer cells can help doctors choose the most effective drugs. Researchers will compare the model's predictions to how the patient actually responds to treatment. About 250 adults with non-small cell lun…