Shanghai Pulmonary Hospital, Shanghai, China

This study is testing whether adding a traditional Chinese herbal formula called Huanjingjian decoction to standard hormone replacement therapy (HRT) helps women with premature ovarian insufficiency (early menopause). Researchers will compare the herbal formula plus HRT against a…

This study aims to find out if a surgery that removes a smaller piece of the lung (segmentectomy) is as good as the standard surgery that removes a larger lobe (lobectomy) for people with a specific type of early-stage lung cancer. Researchers will enroll 587 patients and randoml…

This study is testing a three-drug combination (JSKN016, toripalimab, and carboplatin) given to patients before they have surgery for stage II or III non-small cell lung cancer. The goal is to see if this treatment can shrink or eliminate the tumor in the lung and nearby lymph no…

This study is testing whether adding a targeted drug called Bozitinib to standard chemotherapy helps shrink tumors before surgery for people with a specific genetic change (MET-altered) in their stage IIA-IIIC non-small cell lung cancer. The main goal is to see if this combinatio…

This study is testing whether a comprehensive prevention plan can help Chinese patients with advanced lung cancer better tolerate treatment with the drug amivantamab. The plan aims to reduce common side effects like skin rash, infusion reactions, and blood clots. Researchers will…

This study is testing whether adding a new drug called acetohydroxamic acid (AHA) to existing shorter treatment regimens can help people with multidrug-resistant tuberculosis. Researchers will enroll 120 participants to see if the combination is safe and effective at clearing the…

This study is testing whether adding the targeted drug ensartinib after standard chemoradiation can better control advanced, inoperable lung cancer in patients with a specific genetic change (ALK mutation). It will involve about 45 patients who have completed initial treatment wi…

This study aims to develop a better method for finding lung cancer early by combining two tests: a low-dose CT scan and a new blood test that looks for cancer signals. It will enroll 14,300 people, including those with and without cancer, to see if using both tests together is mo…

This study is testing if a local anesthetic (bupivacaine) injected into the chest cavity can better control pain after minimally invasive chest surgery. Researchers will compare two different strengths of the drug against a placebo (saltwater) in 249 patients. The main goal is to…