Shanghai Pulmonary Hospital, Shanghai, China

This study compares two types of lung cancer surgery for people with a specific kind of lung cancer (adenocarcinoma) that is 2-3 cm in size. One surgery removes a small part of the lung (segmentectomy), while the other removes a larger section (lobectomy). The goal is to see if t…

This study tests whether adding a traditional Chinese herbal formula (Huanjingjian decoction) to standard hormone therapy can improve quality of life for women with premature ovarian insufficiency (early menopause). About 276 women aged 18-39 will take either the herbal formula o…

This study tests whether a drug called bozitinib, combined with chemotherapy, can shrink tumors in people with a specific genetic lung cancer (MET-altered) before they have surgery. About 34 adults with stage IIA to IIIC non-small cell lung cancer will receive the treatment and t…

This study tests whether adding acetohydroxamic acid (AHA) to a short-course drug regimen can safely and effectively treat multidrug-resistant tuberculosis (MDR-TB). About 120 adults with confirmed MDR-TB will receive either AHA or a placebo along with standard short-course antib…

This study tests a special care plan (CEPM) to help manage side effects like rashes and infusion reactions in people with advanced EGFR-mutated lung cancer taking the drug amivantamab. About 122 Chinese patients will take part. The goal is to see if this plan improves quality of …

This study tests a new treatment for people with advanced small-cell lung cancer whose cancer got worse after initial therapy. The treatment combines a chemotherapy drug called nab-paclitaxel with targeted radiation. The goal is to see if this combination can slow cancer growth a…

This study tests whether a combination of three drugs (JSKN016, toripalimab, and carboplatin) given before surgery can eliminate or shrink tumors in people with stage II-III non-small cell lung cancer. About 54 participants will receive the treatment and then have surgery to remo…

This study tests whether taking ensartinib (a targeted pill) after chemoradiation can help people with ALK-mutated stage III lung cancer that cannot be removed by surgery. About 45 adults who have finished chemoradiation without their cancer getting worse will be randomly assigne…

This study tests whether combining a targeted drug (furmonertinib) with local treatments like ablation or radiation can help control early-stage non-small cell lung cancer in people who cannot have surgery or choose not to. About 45 participants with specific EGFR gene mutations …

This study aims to improve early detection of lung cancer by combining CT scans with a blood test that looks for DNA changes. Researchers will enroll 14,300 people aged 40-74 who have been diagnosed with cancer but haven't started treatment yet. The goal is to see if this combine…

This study tests whether injecting a numbing medicine (bupivacaine) into the chest can reduce pain from chest tubes after lung surgery. About 249 adults having minimally invasive lung surgery will receive either a low or high dose of bupivacaine or a placebo. The goal is to find …

This study tests if a painless electrical stimulation treatment, called TEAS, given before lung surgery can prevent the common shoulder pain that often follows. About 216 adults having keyhole lung surgery will be randomly assigned to receive TEAS or standard care. Researchers wi…