Shanghai Pulmonary Hospital, Shanghai, China

This study tests whether combining the drug envolizumab with radiation therapy before surgery can safely shrink tumors in people with locally advanced thymic carcinoma. About 25 adults aged 18-75 with stage III-IVA disease who have not had prior treatment will receive the combina…

This study compares two types of surgery for people with small (≤2 cm) lung adenocarcinoma that does not have aggressive features. One surgery removes only the part of the lung with the tumor (segmentectomy), while the other removes the entire lobe (lobectomy). The goal is to see…

This study tests whether giving a mix of two immunotherapy drugs (sintilimab and IBI310) plus chemotherapy before surgery can shrink tumors in people with stage II-III non-small cell lung cancer. About 54 participants will receive the treatment and then have surgery. The main goa…

This phase II trial tests whether a new drug called IBI363, combined with standard chemotherapy, can shrink stage III non-small cell lung cancer that was initially too advanced to remove with surgery. The goal is to make the tumors operable, then remove them. About 43 adults with…

This study tests whether two drugs, sacituzumab tirumotecan and limertinib, can shrink EGFR-mutant lung cancer enough to allow surgery. About 36 adults with advanced but potentially removable lung cancer will receive the combination before surgery. The goal is to see how many pat…

This study tests a drug called teniposide in people with a fast-growing type of lung cancer (extensive-stage small cell lung cancer) that has a specific gene change (c-Myc-driven). The cancer must have gotten worse after standard treatments. The goal is to see if teniposide can s…

This study tests whether synthetic PET images, created from standard CT scans using artificial intelligence, can accurately diagnose and guide treatment for lung cancer. Researchers will enroll 10,000 people with non-small cell lung cancer to see if this new method matches the qu…

This study compares two drugs, sugammadex and neostigmine, to see which one helps lung function recover better after lung surgery. 240 adults having a specific type of lung surgery will be randomly assigned to receive one of the drugs. The main goal is to measure how well the lun…

This study compares a long-acting painkiller (liposomal bupivacaine) to a standard one (bupivacaine hydrochloride) for numbing nerves between the ribs during lung surgery. About 210 adults having keyhole lung surgery will be randomly assigned to one of three groups: the long-acti…

This study looks at whether a lab-grown model of a patient's own lung cancer cells can help doctors choose the most effective drugs. Researchers will compare the model's predictions with how the patient actually responds to treatment. The goal is to see if this approach can guide…

This study aims to better understand bronchiectasis, a chronic lung disease, in Chinese patients. Researchers will collect data from 1500 adults to identify different disease types and their underlying causes. The goal is to improve diagnosis and tailor treatments for each patien…