New combo therapy shows promise for rare chest cancer
NCT ID NCT06019468
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining the drug envolizumab with radiation therapy before surgery can safely shrink tumors in people with locally advanced thymic carcinoma. About 25 adults aged 18-75 with stage III-IVA disease who have not had prior treatment will receive the combination, then undergo surgery. The goal is to see how many patients have their tumors shrink or disappear, and to establish better treatment standards for this rare cancer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Shanghai Pulmonary Hospital
RECRUITINGShanghai, Shanghai Municipality, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Shorter radiation after thymic tumor surgery may cut side effects
- Fewer radiation sessions may be just as effective for thymic tumors after surgery
- Immune cells engineered to hunt thymus cancer show promise in early trial
- Immunotherapy drug nivolumab tested for rare thymus cancers
- New trial aims to stop thymic cancer return with Chemo-Radiation combo
- Thymoma treatment trial pulled before starting