Shanghai Jiao Tong University School Of Medicine

This early-phase trial tests a new cell therapy (ES-NK cells) in 5 to 9 people with lupus nephritis that hasn't responded to standard treatments. The goal is to see if the therapy is safe and can help control the disease by reducing kidney inflammation. Participants receive one o…

This study tests a three-drug combination (aclarubicin, azacitidine, venetoclax) for people with acute myeloid leukemia (AML), including those newly diagnosed or whose cancer has returned. The goal is to find the safest dose and see if the combo improves remission rates. About 11…

This study tests a new chemotherapy combination called CAOP for elderly patients (65+) with a rare type of lymphoma called peripheral T-cell lymphoma (PTCL). The goal is to see if replacing a standard drug with a less heart-toxic one can still control the cancer while being safer…

This early-phase study tests a new treatment called VGN-Ex05e for children with autism who have severe, treatment-resistant self-injury or aggression. Six participants aged 7 to 18 will receive a single injection into a brain area linked to reward and behavior. The main goal is t…

This early study will test whether adding a new drug (CS0159) to a standard diabetes medication (semaglutide) can help people with fatty liver disease, obesity, and type 2 diabetes lose weight and improve their health. About 30 adults will take the combination or a placebo for 12…

This early-stage study tests whether adding an experimental drug (VIC-1911) to standard medications can prevent graft-versus-host disease (GVHD) in children aged 8-18 who receive a stem cell transplant from a half-matched donor. GVHD occurs when donor cells attack the child's bod…

This study tests a new combination of drugs (CAOP) for people with cutaneous T-cell lymphoma (CTCL) that has come back or not responded to prior treatment. The goal is to find the safest dose and see if the treatment shrinks tumors. About 37 adults aged 60 and older will take par…

This study tests whether a drug called chiglitazar, combined with anti-inflammatory and liver-protecting treatments, can help people with both type 2 diabetes and a serious fatty liver disease called MASH. About 300 adults will receive either the combination or a placebo to see i…

This study aims to create a better way to detect early stomach cancer during endoscopy. Researchers will develop a diagnostic model using narrow band imaging to help doctors, especially those with less experience, identify cancerous lesions more accurately. The study will involve…

This study tests whether a capsule form of hyoscine butylbromide can reduce stomach movements during painless gastrointestinal endoscopy, making it easier for doctors to see and work. About 74 adults scheduled for upper GI endoscopy will receive either the drug or a placebo. The …

This study tests whether an artificial intelligence (AI) system can help doctors in non-academic hospitals accurately diagnose small colon polyps (≤5mm) during a colonoscopy. If successful, many polyps could be removed and discarded without sending them to a lab, saving time and …

This study looks at whether a magnetically-controlled capsule (a tiny camera you swallow) can safely and effectively check the stomach after surgery in elderly patients or those with other health problems. About 120 people who have had stomach cancer surgery will either get the c…

This study looks at fluid from peritoneal dialysis to find early warning signs of peritoneal fibrosis, a scarring condition. Researchers will analyze genetic and metabolic markers in the fluid of 55 people, including dialysis patients and healthy volunteers. The goal is to better…