Second Affiliated Hospital Of Nanchang University

This study tests if transplanting healthy bacteria onto the eye's surface can improve symptoms of dry eye disease. About 40 adults with moderate to severe dry eye will receive either the bacteria transplant or a standard treatment. The goal is to see if this approach is safe and …

This study tests whether a weekly semaglutide injection works better than a calorie-restricted diet for people with type 2 diabetes and fatty liver disease. Over 12 weeks, researchers will measure changes in blood sugar, weight, inflammation, and liver fat. The goal is to find th…

This study looks at whether adding the antidepressant olanzapine to standard immunotherapy can help people with advanced non-small cell lung cancer live longer. About 156 adults with a specific type of lung cancer (EGFR mutation-negative) will either get immunotherapy alone or wi…

This study tests whether a probiotic called MR-61 can help slow the worsening of myopia (nearsightedness) in children aged 3 to 18. Researchers will compare changes in vision and eye measurements between those taking the probiotic and those taking a placebo over time. The goal is…

This study tests a combination of higher-dose targeted therapy, an anti-angiogenesis drug, and chemotherapy injected into the spine for people with advanced lung cancer that has spread to the lining of the brain and is no longer responding to standard treatment. About 30 adults w…

This study tests whether a special type of radiation (SFRT) combined with the immunotherapy drug tislelizumab and standard chemotherapy can shrink stage III lung cancer enough to allow surgery. About 30 adults with initially unresectable non-small cell lung cancer will receive th…

This study tests whether draining fluid from the spine and injecting a clot-busting drug (urokinase) early after a severe brain bleed improves recovery. About 424 adults with a first-time severe aneurysm bleed will be randomly assigned to get either this treatment or a placebo, a…

This study tests a two-step treatment for people with large, relapsed solid tumors that cannot be removed by surgery. First, a special type of radiation is given, followed by standard radiation combined with two immunotherapy drugs (iparomlimab and tuvonralimab). The goal is to s…

This study looks at whether a procedure called superselective adrenal arterial embolization can improve blood vessel function in people with primary aldosteronism, a condition where the adrenal glands produce too much of the hormone aldosterone, leading to high blood pressure. Th…

This study tests whether a computer program (AI) can accurately predict the best lens size for people having surgery to correct nearsightedness. Researchers will compare the AI's predictions to actual results in 326 patients. The goal is to improve surgical outcomes and reduce co…

This study is testing whether a computer program (a type of AI) can predict complications during SMILE eye surgery and how well patients see afterward. About 1250 people with nearsightedness will have their surgery data analyzed by the AI. The goal is to see if the AI can accurat…

This study tests a nursing program based on the ITHBC theory to help patients manage their own recovery after varicose vein surgery. About 104 adults who are having their first surgery for varicose veins will take part. The program focuses on improving self-care skills, confidenc…

This study tests if a new device called AccuSafe guidewire is safer and more effective than the traditional needle used to cross the wall between heart chambers during a procedure for atrial fibrillation (an irregular heartbeat). About 144 adults with atrial fibrillation will be …

This study tests whether adding a long-acting painkiller (liposomal bupivacaine) to a standard steroid injection during shoulder surgery helps reduce pain and stiffness better than the steroid alone. About 70 adults with rotator cuff tears and shoulder stiffness will be randomly …

This study aims to understand what factors affect vision sharpness after a type of laser eye surgery called SMILE, where a tiny piece of the lens is intentionally left in the eye. Researchers will measure changes in the eye's natural imperfections before and after surgery in 33 a…

This study aims to create a smart computer model that can help doctors better diagnose and predict recovery for people with a type of stroke called spontaneous intracerebral hemorrhage. Researchers will use data from over 7,000 patients to train the AI. The goal is to improve acc…

This study is following 5,000 people who had a brain bleed from a burst aneurysm. Researchers are collecting data to find out which factors lead to complications, disability, or death. The goal is to build better prediction tools to help doctors and patients make informed decisio…