Second Affiliated Hospital Of Nanchang University

This study tests whether adjusting the dose of mavacamten based on heart pumping strength can further reduce the blockage of blood flow in people with obstructive hypertrophic cardiomyopathy. Participants are adults who have been on a stable mavacamten dose for at least 12 weeks …

This trial investigates whether adding early lumbar drainage to standard care (a drain in the head plus clot-dissolving medication) improves long-term outcomes for people with bleeding into the brain's fluid-filled spaces. The study includes adults aged 18 to 85 who have had a fi…

This phase 2 trial tests whether adding two immunotherapy drugs (iparomlimab and tuvonralimab) to a special type of radiation and standard chemotherapy can help people with advanced, bulky head and neck cancer live longer without the disease getting worse. The study will enroll 2…

This study tests whether a non-invasive brain stimulation technique called rTMS can improve symptoms of Alzheimer's disease by regulating the 'gut-brain axis'—the link between gut bacteria and the brain. Researchers will treat 200 Alzheimer's patients with either real or sham rTM…

This study tests whether giving a powerful cholesterol-lowering drug (recaticimab) early after a heart attack can safely reduce future heart problems. About 2,442 adults who recently had a heart attack will receive the drug or standard care. The goal is to see if this approach lo…

This study compares deep sedation using a combination of three drugs (dexmedetomidine, remimazolam, and remifentanil) to standard general anaesthesia for patients undergoing a procedure to treat atrial fibrillation (an irregular heartbeat). The goal is to see if deep sedation can…

This study tests a safe, non-invasive therapy that uses gentle pressure on the arms to improve sleep and mood in people who have had a stroke and suffer from insomnia. The treatment, called remote ischemic adaptation, aims to help the brain recover by briefly restricting and rest…